DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bigmax and sre1

DIOPT Version :9

Sequence 1:	NP_651556.2	Gene:	bigmax / 43293	FlyBaseID:	FBgn0039509	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_595694.1	Gene:	sre1 / 2540730	PomBaseID:	SPBC19C2.09	Length:	900	Species:	Schizosaccharomyces pombe

Alignment Length:	227	Identity:	46/227 - (20%)
Similarity:	80/227 - (35%)	Gaps:	72/227 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSDNNNALATKEDVFGMEHDQDHTSKHYSRCSSAGSTHTPNSSAHN---SDDDDDS--------- 53
            ||:....|.|:|.:..|:                 :|..|..||..   |...:||
pombe   188 MSNPEVKLKTEEIITPMD-----------------TTCKPEPSAKKIKLSPSSEDSCSIPETLPF 235

  Fly    54 --GDARHSAAANSTLSY-----KERRREAHTQAEQKRRDAIKKGYDSLQELVP--------RC-- 101
              ..:|.|.:.:.|..:     .:.::.||...|::.|..:......|::.||        ||
pombe   236 SAPKSRGSLSPSETPDFVAGPGGKPKKTAHNMIEKRYRTNLNDRICELRDAVPSLRAAAALRCGN 300

  Fly   102 --QPNDSSGY----KLSKALILQKSIEYIGYLN------QQKLKQEDEGSALQKE---------- 144
              ...|..|.    ||:|..||.|:.|||.:|.      |:..||..:..|..::
pombe   301 SLDDEDLGGLTPARKLNKGTILAKATEYIRHLEAKNKELQKTNKQLSDRLAFYEDPSMAPPSNDT 365

  Fly   145 --VTALRIIKNGYENMLQHQQANPGPEEARLT 174
              |.::.::.:...::  ||.:.|...:...|
pombe   366 RAVNSVNVVSSSDYSV--HQSSRPNLTQRAFT 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bigmax	NP_651556.2	HLH	69..130	CDD:238036	21/82 (26%)
sre1	NP_595694.1	HLH	261..333	CDD:278439	20/71 (28%)
sre1	NP_595694.1	DUF2014	517..766	CDD:286510
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870