DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bigmax and mlx

DIOPT Version :9

Sequence 1:	NP_651556.2	Gene:	bigmax / 43293	FlyBaseID:	FBgn0039509	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_004918784.1	Gene:	mlx / 101732928	XenbaseID:	XB-GENE-970062	Length:	226	Species:	Xenopus tropicalis

Alignment Length:	216	Identity:	101/216 - (46%)
Similarity:	142/216 - (65%)	Gaps:	15/216 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SRCSSAGST---HTPNSSAHNSDD------DDDSGDARHSAAANSTLSYKERRREAHTQAEQKRR 84
            ||.:|.|||   ..||::.:..|:      ||:..|.|.....|   .||:|||.||||||||||
Frog     9 SRANSIGSTSASSVPNTACNMMDNACSLTSDDEDSDDRQETIKN---DYKDRRRRAHTQAEQKRR 70

  Fly    85 DAIKKGYDSLQELVPRCQPNDSS--GYKLSKALILQKSIEYIGYLNQQKLKQEDEGSALQKEVTA 147
            ||||||||.||.:||.||..|.:  ..|||||::|||:|:||.:||::|.||||:.|.|:|||.|
Frog    71 DAIKKGYDDLQCIVPTCQQQDIAIGTQKLSKAVVLQKTIDYIQFLNKEKKKQEDDVSTLRKEVMA 135

  Fly   148 LRIIKNGYENMLQHQQANPGPEEARLTDEAKFQVFQAIMEEMFETF-QHIPMENFKQLTTGIIPW 211
            |:|:|:.||.:::..|.|......::.||.||:|||.||:.:|.|| ..:.:.:|::|:..:..|
Frog   136 LQIMKSNYEQIVKAHQNNLHEGTDQVPDEMKFRVFQGIMDSLFHTFNSSVSVNSFQELSACVFAW 200

  Fly   212 LEEHCKPHILRNILSRTLQQM 232
            :||||||..|::|:.|.|.|:
Frog   201 IEEHCKPQTLQDIVIRFLHQL 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bigmax	NP_651556.2	HLH	69..130	CDD:238036	42/62 (68%)
mlx	XP_004918784.1	bHLHzip_Mlx	57..133	CDD:381530	49/75 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I7366
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H7969
Inparanoid	1	1.050	184	1.000	Inparanoid score	I3830
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1234389at2759
OrthoFinder	1	1.000	-	-		FOG0007499
OrthoInspector	1	1.000	-	-		oto102924
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6384
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060