DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)mbt and Samd7

DIOPT Version :9

Sequence 1:	NP_733209.1	Gene:	l(3)mbt / 43288	FlyBaseID:	FBgn0002441	Length:	1477	Species:	Drosophila melanogaster
Sequence 2:	NP_083765.2	Gene:	Samd7 / 75953	MGIID:	1923203	Length:	445	Species:	Mus musculus

Alignment Length:	342	Identity:	81/342 - (23%)
Similarity:	130/342 - (38%)	Gaps:	79/342 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1130 PPGYLQPKSVMPC-DVEGCRGFGNAKRFNLNVHALRECCPYAPENWRQ-WRSKT----VKPPRVA 1188
            |.|: |.:|.:|. ||...|......:.|..:.|.|   |:..|.|.| :|.:.    .|||...
Mouse   140 PTGF-QGRSTLPASDVHLHRSTFRHLQGNPILLATR---PHFTECWGQKYRLRRGAVYQKPPESD 200

  Fly  1189 PENIRRGWAKKTKRACS----EAKQAIKE-----DSQQEIVYPKVAEVVQAKRKTSPCEEKVVKK 1244
            .|:.:....:|:.....    |.::.||:     |:||:   |:||:........:|..|....:
Mouse   201 TESFKSQAEEKSSSQMPTLSYEEEEYIKDPDIEVDNQQK---PRVADGKPTTVPANPHGELHTHQ 262

  Fly  1245 QKQMQKE----EDAEQVPDE-------------RSLAIARSFVKDYGPQFLP---NYRLWQLNSA 1289
            :|....|    :|.:..|.|             |.::|            ||   .:....|...
Mouse   263 RKPSSLEANAWDDGKGKPSEQVYEGCDGKNGVFRPVSI------------LPLSGTHEQVALREN 315

  Fly  1290 FKLDDVRTNPLHWTSWDVCEYIERALDSTDIAKVIFEQDIDGRALLMLGRKELDTYLKLKVGPAV 1354
            ..|.|::    .||..||..:|......:|.|:|..:..|||..|.:|..:.|...:.||:|||:
Mouse   316 CSLSDIQ----KWTVDDVYNFIRSLPGCSDYAQVFKDHAIDGETLPLLTEQHLRGTMGLKLGPAL 376

  Fly  1355 KLYSLILNLRIAVVCKFDSKNIELESNTAGPIQREMDTPVSAIKQLPEQSQTNGYKTDHDQELSE 1419
            |:.|.:......:.||   |...|.::.    ::..|.|......|...|.::|        ||.
Mouse   377 KIQSQVSQHVGNMFCK---KLPSLPTHA----RQAFDQPADTSPLLDMSSWSDG--------LSI 426

  Fly  1420 SGDDD------DDEDVM 1430
            .|..|      .::|||
Mouse   427 PGPQDLLSPKRTEQDVM 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	MBT	822..918	CDD:214723
		MBT	929..1028	CDD:214723
		MBT	1038..1130	CDD:214723	81/342 (24%)
		SAM_PNT	1279..1366	CDD:280377	25/89 (28%)
Samd7	NP_083765.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	193..282		20/91 (22%)
		SAM_Samd7,11	321..388	CDD:188978	21/70 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	425..445		6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839851
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840