DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)mbt and THAP10

DIOPT Version :9

Sequence 1:	NP_733209.1	Gene:	l(3)mbt / 43288	FlyBaseID:	FBgn0002441	Length:	1477	Species:	Drosophila melanogaster
Sequence 2:	NP_064532.1	Gene:	THAP10 / 56906	HGNCID:	23193	Length:	257	Species:	Homo sapiens

Alignment Length:	127	Identity:	28/127 - (22%)
Similarity:	38/127 - (29%)	Gaps:	50/127 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   367 AKPSIKTAPKPTPK--------------------------PLEMSVNGPAKEKKAPAKE------ 399
            |.|::...|.|.||                          |..:|...|...|:|.|.:
Human    85 AVPTLHRVPAPAPKRGEEGDQAGRLDTRGELQAARHSEAAPGPVSCTRPRAGKQAAASQITCENE 149

  Fly   400 --QKQKTMDKPP-VVKEIAQHTPCGPKELPKLKRSKSFVSNHPASPVANNERRH-SVAIMAK 457
              |.|...|.|. .|..:..|...||.              |.::.::....|| ||.|.||
Human   150 LVQTQPHADNPSNTVTSVPTHCEEGPV--------------HKSTQISLKRPRHRSVGIQAK 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	MBT	822..918	CDD:214723
		MBT	929..1028	CDD:214723
		MBT	1038..1130	CDD:214723
		SAM_PNT	1279..1366	CDD:280377
THAP10	NP_064532.1	THAP	4..90	CDD:214951	2/4 (50%)
THAP10	NP_064532.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	154..178		7/37 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149819
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930