Protein Alignment l(3)mbt and sfmbt2

DIOPT Version :10

• Sequence 1: NP_733209.1
• Gene: l(3)mbt / 43288
• FlyBaseID: FBgn0002441
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: XP_005164891.1
• Gene: sfmbt2 / 555450
• ZFINID: ZDB-GENE-041210-196
• Length: 861
• Species: Danio rerio
• Alignment Length: 865
• Identity: 174/865 - (20%)
• Similarity: 277/865 - (32%)
• Gaps: 327/865 - (37%)

  Fly   819 FRWSEYLKSKGKDVAAPIHLFLNPFPIS-PNCFEIGMKLEAIDPENCSLFCVCSIVEVRGYRLKL 882
            |.|.|||:..|. .||| |.......:| .:.|:.|||||..:..:...:.|.:|:...|..|.|
Zfish    10 FNWEEYLEDTGA-TAAP-HTSFRHVELSLQSSFQPGMKLEVANKGSVDTYWVATIITTCGQLLLL 72

  Fly   883 SFDGYSS--MYDFWVNADSQDIFPPGWCDETARVLQAPKDYN-------SERFS-WSRYLVK--T 935
            .:.||..  ..|||.:..:.::.|.|||.:..:.||.|:| |       .|::| |:.:|:|  |
Zfish    73 RYCGYGEDRKADFWCDVMTAELHPVGWCAQNDKTLQPPED-NVYLRAAIKEKYSDWTEFLIKELT 136

  Fly   936 GGKAAPRALF-GHLNMQQQMDVRNGFAVGMHLEAEDLNDTGKICVATVTDILDERIRVHFDGWDD 999
            |.:.||..|. |.|..:..:|:   ...|..||..|.::........|...:..|:.:.:.|.:|
Zfish   137 GSRTAPANLLEGPLRGKNTVDL---IMEGSILELRDASEPSVYWATQVQRNVGGRLCLSYVGLND 198

  Fly  1000 -CYDLWVHITSPYIHPCGWHEGRQQLIVPP----DYQKSAFIWDDYISEVGGMAASKELFTPRQP 1059
             .|.:|:......:.|.||.:.....:.||    |.:.|: .|...:.|....|.:..|     |
Zfish   199 PSYYMWMFYLDTRLRPLGWAKENNLPMKPPTDLCDLRSSS-EWTTALDEATAEALNNPL-----P 257

  Fly  1060 ME------------YQERMKLEVVDQRNPCLIRPATVV-TRKGYRVQLHLD-------------- 1097
            :|            ::..||||:|....|..|.|.:|. ....|..|:.:|
Zfish   258 LEVFKDHADLHTHSFRAGMKLEMVSPVEPFHICPVSVTKVYNEYHFQITVDDLTADATPTSAVCH 322

  Fly  1098 -----------------------------------------------CWPTEYY-------FWLE 1108
                                                           |:|....       .|||
Zfish   323 AESPGILPVQWCLKNGVELERPRGFETQDFDWADYLKHTSTEAAPDACFPNASQSRGFCKDMWLE 387

  Fly  1109 DDSP----------------------------------------DLHPIGWCEAT----SHELET 1129
            ..:|                                        ::.|:|||||.    :|.|:|
Zfish   388 AVNPLHPAELCVARITQVKGCLLWLRLEGLTKPLPDCIVDVESMNIFPVGWCEANGYPLTHSLKT 452

  Fly  1130 ------------PPGYLQPK----------SVMPCD---VEG---C-RGFGNAKRFN---LNVHA 1162
                        |...|.|.          |..|.|   |.|   | :.|.|.:.|:   ||...
Zfish   453 VCLPQKKIAVVQPEKQLAPSQSPDIPISLCSSAPMDSGLVNGKYCCSQLFINHRCFSGPYLNKGR 517

  Fly  1163 LRE---------CCPYAPENWRQWRSKTVKPPRV--------------APENIRRGWAKKT---- 1200
            :.|         |.....|......:...||.||              ..|.::..:..|:
Zfish   518 IAELPKAVGPGKCAVVLKEILTMLINSAYKPGRVLRELQMVEDPQWNCQEETLKAKYKGKSYRST 582

  Fly  1201 --------------KRAC------------------------SEAKQAIKEDSQQEIVYPKVAEV 1227
                          :|.|                        |:.|.......::::..|.:.|.
Zfish   583 MRIVRTADQVSEFCRRVCERLQCCLNLFGPTFVSDKCPENCSSQTKTKYTYYKKRKVGRPSLGEN 647

  Fly  1228 VQAKRKTSPCEEKVVKKQKQMQK--------------------------EEDAEQVPDERSLAIA 1266
            .|....:.|...:..:|...:||                          :||.|:...|.|.:..
Zfish   648 AQDGDLSKPARRRKKRKAIFVQKKRRSSIVGYHTTESPQDSDYNYDEDEDEDFEEWGSEASSSSL 712

  Fly  1267 RSFVKDYGPQFLP-----------------------------------NYRLWQL--NSAFKLDD 1294
            |.....:..  ||                                   :|...|:  ::..|::.
Zfish   713 REEASAHNS--LPRRGRPPRRAALQRRMTHPGSETSDRISPRRTTRSVSYSQNQMARDTNVKMES 775

  Fly  1295 VR--------TNPLHWTSWDVCEYIERALDSTDIAKVIFEQDIDGRALLMLGRKELDTYLKLKVG 1351
            ..        ||||.|:..||.::| .:.|...:||:..||||||:|||:|....:...:.||:|
Zfish   776 TEEEDRLVLDTNPLQWSVSDVVDFI-TSTDCASLAKIFQEQDIDGQALLLLTLPTVQECMDLKLG 839

  Fly  1352 PAVKLYSLILNLRIAVVCKF 1371
            ||:||...|..:::|...::
Zfish   840 PAIKLCHQIERVKVAFYSQY 859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	PRK10819	<332..>427	CDD:236768
		MBT_L3MBTL1-like_rpt1	846..945	CDD:439091	35/111 (32%)
		MBT_L3MBTL1-like_rpt2	957..1045	CDD:439092	19/92 (21%)
		MBT_L3MBTL1-like_rpt3	1058..1130	CDD:439093	29/208 (14%)
		SAM_PNT	1278..1367	CDD:460486	34/133 (26%)
sfmbt2	XP_005164891.1	MBT	37..137	CDD:459242	30/100 (30%)
		MBT_SFMBT2_rpt2	156..253	CDD:439104	21/100 (21%)
		MBT	270..362	CDD:459242	12/91 (13%)
		MBT_SFMBT2_rpt4	379..469	CDD:439108	14/89 (16%)
		SLED	498..612	CDD:463469	17/113 (15%)
		SAM_Scm-like-4MBT1,2	777..861	CDD:188980	30/84 (36%)