Protein Alignment l(3)mbt and Scm

DIOPT Version :10

• Sequence 1: NP_733209.1
• Gene: l(3)mbt / 43288
• FlyBaseID: FBgn0002441
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: NP_731385.1
• Gene: Scm / 41168
• FlyBaseID: FBgn0003334
• Length: 877
• Species: Drosophila melanogaster
• Alignment Length: 946
• Identity: 209/946 - (22%)
• Similarity: 325/946 - (34%)
• Gaps: 278/946 - (29%)

  Fly   606 SSSSSGSHASEMSPPPKLADPKPSSPPAKNAK-KANDHDANPSPSSKTNDFKKSMMQNLNMLK-- 667
            ||:||||::         |.|..|:....:|. .|:....:.||.|.|:.......:.....:
  Fly     7 SSTSSGSNS---------AAPGASTNATSSASASASSTSTSASPGSTTSPASTQRQRGRPAKRAT 62

  Fly   668 --WRGQQPANLQ----NSTVRFELNEFNFLQINERCQPRQGPAAYFERPLYDRPGRRPSACVHPL 726
              |.|:....||    ..|.:.|.       .:|.|      .|.| |..|.:     .||..
  Fly    63 CTWCGEGKLPLQYVLPTQTGKKEF-------CSETC------IAEF-RKAYSK-----GACTQ-- 106

  Fly   727 LYLCQRCNFHGPAADFLAPH--FCSVGCVRRSQKRRLPQSTQKESKISRTQLEQTAGTAPDLPQK 789
               |......|      ||:  |||:.|:.:.||:..  ||:           .:.|:|..
  Fly   107 ---CDNVIRDG------APNKEFCSIMCMNKHQKKNC--STR-----------HSGGSASG---- 145

  Fly   790 RQTNYKPHKSLSAIQEQLQQRQKDKPRKPFR--------WSEYLKSKGKDVAAPIHLFLNPFPIS 846
                    |.|:..:.:|.......|..||:        |..||:..|.: |||...|.......
  Fly   146 --------KGLAESERKLLASGAPAPTGPFQYESFHVFDWDAYLEETGSE-AAPAKCFKQAQNPP 201

  Fly   847 PNCFEIGMKLEAIDPENCSLFCVCSIVEVRGYRLKLSFDGYSSMYDFWVNADSQDIFPPGWCDET 911
            .|.|:|||||||:||.|.:..|:.::|.|.|.||:|..||..|..|||...||.:|...|.|::.
  Fly   202 NNDFKIGMKLEALDPRNVTSTCIATVVGVLGSRLRLRLDGSDSQNDFWRLVDSTEIHAIGHCEKN 266

  Fly   912 ARVLQAPKDYNSERFSWSRYLVK--TGGKAAPRALFGHLNMQQQMDVRNGFAVGMHLEAEDLNDT 974
            ..:||.|..:.....||..||.|  .....||..:|   ..:......|.|.||..|||.|..:.
  Fly   267 GGMLQPPLGFRMNASSWPGYLCKILNNAMVAPEEIF---QPEPPEPEENLFKVGQKLEAVDKKNP 328

  Fly   975 GKICVATVTDILDERIRVHFDGWDDCYDLWVHITSPYIHPCGW------------HEGR------ 1021
            ..||.|||..|.|::|.|.||||...:|.|.:..|..|.|.||            |:.|
  Fly   329 QLICCATVDAIKDDQIHVTFDGWRGAFDYWCNYRSRDIFPAGWCARSCHPMQPPGHKSRMDSSSS 393

  Fly  1022 QQLIVPPDYQKSAFIWDDYISEVGGMAASKELFTPRQPMEYQERMKLE----VVDQRNPCLIRPA 1082
            :|....|.|.               :.|..|...|..|.........:    :.:.:.||::...
  Fly   394 KQRCPRPRYT---------------VVAESEAMVPASPATAHFHPNCKGGPFINNSKLPCMVTGP 443

  Fly  1083 TVVTRKGYRVQLHLDCWP-----TEYYFWLEDDSPDLHPIGWCEATSHELETPPGYLQPKSV--- 1139
            |..|.....:|..|....     ::..|.||.|...:...|  :..:.::.:|......:|:
  Fly   444 TYQTLAKLCLQEVLAASTDTQQLSKLLFALEGDVHIVTAAG--KNFTVKIPSPMRMKDDESLAQF 506

  Fly  1140 --------MPC--------DVEGCRGFGNAKRFNLNVHALRECCP-YAPENWRQWRSKTVKP-PR 1186
                    ..|        :.|.|:...|:::..|...|.....| .|.:..||..|.|..| .:
  Fly   507 IETLCTTCRACANLISLVHETEECKKCANSRKRQLTQSATPPSSPVLADKRNRQSNSATTSPSEK 571

  Fly  1187 VAPEN--IRRGWAKKTKRACSEAKQAIKED---------------SQQEIVY--------PKVAE 1226
            :..:.  ::.....|:|.:.:..|:...:.               |..::|.        .:.:.
  Fly   572 IIKQELAVKSPVESKSKTSTNNGKEPASQQNSNHSLNNNNNSASKSSNKVVIKSEPNGANAQTSS 636

  Fly  1227 VVQAKRK-----------------------------TSPCEEKVVKKQKQMQKEED--------- 1253
            ..||.||                             ||.|..........:.....
  Fly   637 TTQALRKVRFQHHANTNTNSSATNGNQDTSQTTHVSTSHCSSSSTSSSTSLAGGSANTSTIGKYL 701

  Fly  1254 ----AEQVPDERSLAIARSFVKDYGPQFL------------------------------------ 1278
                ||..|::.::..:.|:.|  .|..|
  Fly   702 APLVAEVHPEQANVKPSNSYYK--SPTTLSSSASLPTSVSTPFTGCQSASSTALAAGGVTAAKAA 764

  Fly  1279 -------------PNYR-----LWQLNSAFKLDDVRTNPLHWTSWDVCEYIERALDSTDIAKVIF 1325
                         |:|.     :....||.....:|:.|:.||..:|.:|||...:|..:...:|
  Fly   765 TAPAGAAATAGASPSYTAITSPVSTPTSALANSHLRSQPIDWTIEEVIQYIESNDNSLAVHGDLF 829

  Fly  1326 -EQDIDGRALLMLGRKELDTYLKLKVGPAVKLYSLI 1360
             :.:|||:|||:|..:.:..|:.||:|||:|:.:|:
  Fly   830 RKHEIDGKALLLLNSEMMMKYMGLKLGPALKICNLV 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	PRK10819	<332..>427	CDD:236768
		MBT_L3MBTL1-like_rpt1	846..945	CDD:439091	40/100 (40%)
		MBT_L3MBTL1-like_rpt2	957..1045	CDD:439092	33/105 (31%)
		MBT_L3MBTL1-like_rpt3	1058..1130	CDD:439093	12/80 (15%)
		SAM_PNT	1278..1367	CDD:460486	30/138 (22%)
Scm	NP_731385.1	zf-FCS	58..95	CDD:428958	9/49 (18%)
		MBT_dScm_rpt1	196..294	CDD:439097	38/97 (39%)
		MBT_dScm_rpt2	312..383	CDD:439100	28/70 (40%)
		SLED	418..522	CDD:463469	14/105 (13%)
		SAM_Scm	800..870	CDD:188977	25/66 (38%)