Protein Alignment l(3)mbt and sfmbt1

DIOPT Version :10

• Sequence 1: NP_733209.1
• Gene: l(3)mbt / 43288
• FlyBaseID: FBgn0002441
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: NP_001361769.1
• Gene: sfmbt1 / 100145310
• XenbaseID: XB-GENE-984810
• Length: 842
• Species: Xenopus tropicalis
• Alignment Length: 849
• Identity: 176/849 - (20%)
• Similarity: 272/849 - (32%)
• Gaps: 334/849 - (39%)

  Fly   819 FRWSEYLKSKGKDVAAPIHLFLNPFPISPNCFEIGMKLEAIDPENCSLFCVCSIVEVRGYRLKLS 883
            |.|.|||:..| .:|||...|.:......|....||:||........::.:.:|:...|..|.|.
 Frog    20 FNWEEYLEETG-CIAAPHSFFKHVDTSLKNGLSPGMRLEVPHGTESQVYWIANIITTCGKLLLLR 83

  Fly   884 F--DGYSSMYDFWVNADSQDIFPPGWCDETARVLQAPKDYNSERFSWSRYLVK--TGGKAAPRAL 944
            :  .|.....|||.:..:.|:.|.||..:..:.|:.|:....:..:|..:|.:  ||..:||..|
 Frog    84 YLGCGEDRSADFWCDMVTSDLHPLGWAQQNGKSLRPPEGIREKLQNWEEFLAENSTGVSSAPAHL 148

  Fly   945 F-GHLNMQQQMDVRNGFAVGMHLEAEDLNDTGKICVATVTDILDE---RIRVHFDGWDDCYDLWV 1005
            . |....:..:|:   |..|..||.:...|:   .||....:|:.   |:::.::|..||  :|:
 Frog   149 LEGPHRGKDPLDL---FGPGSKLELQHCRDS---IVAWPVRVLENTGGRLQLQYEGVSDC--VWL 205

  Fly  1006 HITSPYIHPCGW---HE------------------------------------------------ 1019
            ....|.:|..||   |:
 Frog   206 FYLHPSLHQVGWAAQHKYDMQPPQAISHLKSEEEWKEILTKWETDPGDCVPAEFFQEQLPLPVHS 270

  Fly  1020 --------------------------------------------------------------GRQ 1022
                                                                          |..
 Frog   271 FLAGMKVEALDPSNPSCFMPATVTKVFSERYFMIEFDDLRPLDSKTSRPLLCHCNSTGIISVGSS 335

  Fly  1023 Q-----LIVPPDYQKSAFIWDDYISEVGGMAASKELFTPRQPME---YQERMKLEVVD---QRNP 1076
            |     |..||.|.:..|.||.|:::..|.||.:..|...||..   :||:||||.|:   |.:.
 Frog   336 QKMGVPLRPPPGYSEEEFDWDKYLTQCEGSAAPESNFPMPQPQSDHVFQEQMKLEAVNPFQQEDI 400

  Fly  1077 CLIRPATVVTRKGYRVQLHL--------DCWPTEYYFWLEDDSPDLHPIGWCEATSHELETPP-- 1131
            |:   |||....|..::|.|        :|       .:..:|.|:.|:||||...|.|..||
 Frog   401 CI---ATVTQVMGPYIRLQLEGSKLPIAEC-------IVHVESMDIFPMGWCETNGHLLCAPPRT 455

  Fly  1132 GYLQPKSVMPCDVE-------GCRGFGNAK----RFNLNVHALRECCPYAPENWRQWRSKTVKPP 1185
            ....||..:....|       ...|....:    :||.|...|   ||....|.|.:....:...
 Frog   456 KVSPPKETVTTQHEKPIPSSKNVNGLSTTEPAPCKFNSNGKYL---CPKIYFNHRCFSGPYLNKG 517

  Fly  1186 RVA--PENIRRG---------------WAKKTKRACSEAKQAIKEDSQQEIVYPKVAEVVQAK-- 1231
            |:|  |:::..|               .|.|..|...|.:  ::|||.    :|:..|.::||
 Frog   518 RIAELPKSVGPGSCVLVLKEVLSLLINAAYKPSRVLRELE--LQEDSS----WPQHTETIKAKYK 576

  Fly  1232 ---------------------RKT-----------------SPCEEK------------------ 1240
                                 |||                 ..|.|.
 Frog   577 GKTYRSTVELVRTSDQVPDFCRKTCLKLECCPNLFGPQMVLDQCSENCSVLTKTKYTHYYGKRRG 641

  Fly  1241 ------------------------------VVKKQKQM---------------QKEEDAEQVPD- 1259
                                          .|.|:|:|               .:|||.|...|
 Frog   642 KNLTNPTGILRSIEAALKKPAKKRRRRKNFFVHKKKRMSTSVDNTPGGSPQGSDEEEDEEDEDDS 706

  Fly  1260 ------------------------ERSLAIARSFVKDYGPQFLPNYRLWQLNSAFKLDD---VRT 1297
                                    |.||    |..|.....|..|.:|...:...:|.:   :.:
 Frog   707 HSKDQQEGSEISGKGSSSTSPTRSEHSL----STEKKRSHLFSDNEKLLTKDIRIELKEPLILDS 767

  Fly  1298 NPLHWTSWDVCEYIERALDSTDIAKVIFEQDIDGRALLMLGRKELDTYLKLKVGPAVKLYSLILN 1362
            :||.||..||.:|| ::.|..::||...||:|||:|||:|....:...:.||:..||:|...|..
 Frog   768 SPLDWTVNDVIQYI-KSTDCANLAKHFQEQEIDGKALLLLTLPAVQDCMDLKLAAAVRLCYHIER 831

  Fly  1363 LRIA 1366
            :::|
 Frog   832 VKLA 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	PRK10819	<332..>427	CDD:236768
		MBT_L3MBTL1-like_rpt1	846..945	CDD:439091	25/102 (25%)
		MBT_L3MBTL1-like_rpt2	957..1045	CDD:439092	28/208 (13%)
		MBT_L3MBTL1-like_rpt3	1058..1130	CDD:439093	27/85 (32%)
		SAM_PNT	1278..1367	CDD:460486	30/92 (33%)
sfmbt1	NP_001361769.1	MBT_SFMBT1_rpt1	47..140	CDD:439101	21/92 (23%)
		MBT_SFMBT1_rpt2	159..253	CDD:439103	19/101 (19%)
		MBT_SFMBT_rpt3	271..362	CDD:439085	10/90 (11%)
		MBT	381..470	CDD:459242	29/98 (30%)
		SLED	499..614	CDD:463469	22/120 (18%)
		SAM_superfamily	758..842	CDD:472832	28/79 (35%)