DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TfIIA-L and AT1G07470

DIOPT Version :9

Sequence 1:	NP_476995.1	Gene:	TfIIA-L / 43284	FlyBaseID:	FBgn0011289	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_001320242.1	Gene:	AT1G07470 / 837259	AraportID:	AT1G07470	Length:	375	Species:	Arabidopsis thaliana

Alignment Length:	431	Identity:	92/431 - (21%)
Similarity:	165/431 - (38%)	Gaps:	130/431 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 TSVLKVYHAVIEDVITNVRDAFLDE-GVDEQVLQEMKQVWRNKLLASKAVELSPDSGDGSHPPPI 69
            |:...||..|||||:..||:.|::. |..|.||.|::.:|..|::.:..:....:......|.|
plant     5 TTTSAVYIHVIEDVVNKVREEFINNGGPGESVLSELQGIWETKMMQAGVLNGPIERSSAQKPTP- 68

  Fly    70 VANNPKSHKAANAKAKKAAAATAVTSHQ-------------HIGGNSSMSSLVGLKSSAGMAAGS 121
              ..|.:|. .|...:........|:..             .:.|.:..||:..:.:.:......
plant    69 --GGPLTHD-LNVPYEGTEEYETPTAEMLFPPTPLQTPLPTPLPGTADNSSMYNIPTGSSDYPTP 130

  Fly   122 GIRNGL-VPIKQEVNSQNPPPLHPTSAASMMQKQQQAASSGQGSIPIVATLDPNRIMPVNITL-- 183
            |..||: :.:|...:...|||...|                            |..:.||:..
plant   131 GTENGVNIDVKARPSPYMPPPSPWT----------------------------NPRLDVNVAYVD 167

  Fly   184 --PSPAGSASSESRVLTIQVPASALQENQLTQILTAHLISSIMSLPTTLASSVLQQHVNAALSSA 246
              ..|....|::.....:.||:|..::...:   :||..:. .|:|.       |...:.|:..|
plant   168 GRDEPERGNSNQQFTQDLFVPSSGKRKRDDS---SAHYQNG-GSIPQ-------QDGASDAIPEA 221

  Fly   247 NHQKTLAAAK---------------------QLDGAL-DSSDE-----------DESEESDD--- 275
            |.:  .||.:                     |:||.: |..||           ..:||.::
plant   222 NFE--CAALRITYVGDRKIPRDLIGSSSKIPQVDGPMPDPYDEMLSTPNIYSYQGPNEEFNEART 284

  Fly   276 ------------NIDND---DDDDLDKDDDEDAEHEDAAEEEPLNSEDDVTDEDSAEMFDTDNVI 325
                        .:.||   ||::|..:||:|               |::.|.:|.|..:|.:::
plant   285 PAPNEIQTSTPVAVPNDIIEDDEELLNEDDDD---------------DELDDLESGEDMNTQHLV 334

  Fly   326 VCQYDKITRSRNKWKFYLKDGIMNMRGKDYVFQKSNGDAEW 366
            :.|:||:||::::||..||||||::..||.:|.|:.|:.::
plant   335 LAQFDKVTRTKSRWKCSLKDGIMHINDKDILFNKATGEFDF 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TfIIA-L	NP_476995.1	TFIIA_alpha_beta_like	8..>62	CDD:199899	17/54 (31%)
		TFIIA	11..366	CDD:281188	91/424 (21%)
		TFIIA_alpha_beta_like	<306..366	CDD:199899	23/59 (39%)
AT1G07470	NP_001320242.1	TFIIA	10..375	CDD:397322	91/424 (21%)
AT1G07470	NP_001320242.1	TFIIA_alpha_beta_like	<330..375	CDD:199899	19/44 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2652
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2380
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1443035at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2549
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12694
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1433
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	9.020