Protein Alignment TfIIA-L and Gtf2a1l

DIOPT Version :10

• Sequence 1: NP_476995.1
• Gene: TfIIA-L / 43284
• FlyBaseID: FBgn0011289
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_076119.2
• Gene: Gtf2a1l / 71828
• MGIID: 1919078
• Length: 468
• Species: Mus musculus
• Alignment Length: 500
• Identity: 146/500 - (29%)
• Similarity: 212/500 - (42%)
• Gaps: 179/500 - (35%)

  Fly     8 VLKVYHAVIEDVITNVRDAFLDEGVDEQVLQEMKQVWRNKLLASKAVE----------------- 55
            |.|:|.:||||||..|||.|.:||::||||:::|::|..|:|.|||.|
Mouse     7 VPKLYQSVIEDVIEGVRDLFAEEGIEEQVLKDLKKLWETKVLQSKATEDFFRNSTQVPLLTLQLP 71

  Fly    56 ------LSPDSG----DGSHPPPIVANNPKSHKAANAKAKKAAAATAVTSHQHIGGNSSMSSLVG 110
                  |.|::.    .|...|..   .|:....||..|..|.|...:    |:
Mouse    72 HALPPALQPEASLLIPAGRTLPSF---TPEDLNTANCGANFAFAGYPI----HV----------- 118

  Fly   111 LKSSAGMA---AGSGIRNGLVPIKQEVNS------QNP------------------PPLHPTSAA 148
               .||||   |...:....||:.....|      |:|                  |.|||.|..
Mouse   119 ---PAGMAFQTASGHLYKVNVPVMVTQTSGRTEILQHPFQQVLQQLGQPLVIQTTVPTLHPCSLQ 180

  Fly   149 SMMQKQQQAASSGQGSIPIVATLDPNRIM---PVNITLPSPAGSASSESRVLT------------ 198
            :..:|          |:.:.|.|.|..|:   ||:.|   ...:|:|:.|:|.
Mouse   181 AATEK----------SLRMEAVLQPPPILHPPPVDRT---HVENAASDRRLLPGNELRPQESSPY 232

  Fly   199 IQVPA------SALQENQLTQIL--TAHLISSIMSLPTT----------LASSVLQQHVNAALSS 245
            :.:|.      :||.|:.|..:|  :|.|..::.|.|.:          |..|.||. :..::..
Mouse   233 LSLPGVGFPPQAALTESSLEPVLGVSASLTQNLHSDPFSQGPPGPLHHHLLESQLQS-LKDSIYG 296

  Fly   246 ANHQKTLAAAK-------------------------------QLDGALDSS---------DEDES 270
            .:..|.|..|:                               |:||..|:|         |.||:
Mouse   297 CDSTKQLRKAEEPSSLRVSEKNCTSERDLNIRVTDDDINEIIQIDGTGDNSSTEEMGSIRDADEN 361

  Fly   271 E-------------ESDDNIDNDDDDDLDKDDDEDAEHE-DAAEEEPLNSEDDVTDEDSAEMFDT 321
            |             |..|::.| :|...:..|:||  |: :|.||:||||.|||:::|..::|||
Mouse   362 EFPGIIDAGDLNVLEEVDSVSN-EDSTANSSDNED--HQINAPEEDPLNSGDDVSEQDVPDLFDT 423

  Fly   322 DNVIVCQYDKITRSRNKWKFYLKDGIMNMRGKDYVFQKSNGDAEW 366
            :||||||||||.||:|:||||||||:|...|:||||.|:.|:|||
Mouse   424 ENVIVCQYDKIHRSKNRWKFYLKDGVMCFGGRDYVFAKAIGEAEW 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfIIA-L	NP_476995.1	TFIIA	11..366	CDD:460829	142/495 (29%)
Gtf2a1l	NP_076119.2	TFIIA	10..468	CDD:460829	142/495 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	215..236		2/20 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	379..416		17/39 (44%)