DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pll and KIN1

DIOPT Version :9

Sequence 1:	NP_001263008.1	Gene:	pll / 43283	FlyBaseID:	FBgn0010441	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_010407.1	Gene:	KIN1 / 851700	SGDID:	S000002529	Length:	1064	Species:	Saccharomyces cerevisiae

Alignment Length:	466	Identity:	90/466 - (19%)
Similarity:	174/466 - (37%)	Gaps:	133/466 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 SQKQRGRSASNEFLNIWGGQYNHTVQTLFALFKKLKLHNAMRLIKDYVSEDLHKYIPRSVPTISE 138
            :|:..|.|.||..         ||..:..|       ...:|::.....:...:..|...|  ::
Yeast    16 NQQDDGNSESNSM---------HTQPSTMA-------PATLRMMGKSPQQQQQQNTPLMPP--AD 62

  Fly   139 LRAAPDSSAKVNNGPPFPSS--------SGVSNSNNNRTSTTATEEIPSLESLGNIHISTVQRAA 195
            ::.|       |||....:.        .|.|..|..:.:||:...:.|.:.:..      |...
Yeast    63 IKYA-------NNGNSHQAEQKERQVELEGKSRENAPKPNTTSQSRVSSSQGMPK------QFHR 114

  Fly   196 ESLLEIDYAELENATDGWSPDNRLGQGGFGDVYRGKWKQLD--VAIKVMNYRS------------ 246
            :||.:.::.|            .:|.|..|.|...|.:..:  .|:|::|..:
Yeast   115 KSLGDWEFVE------------TVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPP 167

  Fly   247 PNIDQKMVELQQ----------------SYNELKYLNSIRHDNILALYGYSIKGGKPCLVYQLMK 295
            |..:|.::|.|:                |..::.|     |.:|..|:..........::::.:.
Yeast   168 PKNEQDVLERQKKLEKEISRDKRTIREASLGQILY-----HPHICRLFEMCTLSNHFYMLFEYVS 227

  Fly   296 GGSL------EARLRAHKAQNPLPALTWQQRFSISLGTARGIYFLHTARGTPLIHGDIKPANILL 354
            ||.|      ...:|.|:|:            ..:.|.|..:.:||   ...::|.|:|..||::
Yeast   228 GGQLLDYIIQHGSIREHQAR------------KFARGIASALIYLH---ANNIVHRDLKIENIMI 277

  Fly   355 DQCLQPKIGDFGLVREGPKSLDAVVEVNKVFGTKIYLPPEFRNFRQLSTG--VDVYSFGIVLLEV 417
            ....:.||.||||    ....|:..:::...|:..:..||....... ||  |||:|||:||..:
Yeast   278 SDSSEIKIIDFGL----SNIYDSRKQLHTFCGSLYFAAPELLKANPY-TGPEVDVWSFGVVLFVL 337

  Fly   418 FTGRQVTDRVPENETKKNLLDYVKQQWRQNRMELLEKHLAAPMGKELDMCMCAIEAGLHCTALDP 482
            ..|     :||.::...::|   .::.:|.::| ..:||:..:...|...:          .:||
Yeast   338 VCG-----KVPFDDENSSVL---HEKIKQGKVE-YPQHLSIEVISLLSKML----------VVDP 383

  Fly   483 QDRPSMNAVLK 493
            :.|.::..|::
Yeast   384 KRRATLKQVVE 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_001263008.1	Death_Pelle	32..128	CDD:260021	9/53 (17%)
		STKc_IRAK	219..498	CDD:270968	65/313 (21%)
		TyrKc	219..495	CDD:197581	65/313 (21%)
KIN1	NP_010407.1	STKc_Kin1_2	118..398	CDD:270979	66/333 (20%)
KIN1	NP_010407.1	MARK_C_like	890..1062	CDD:213377
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000