DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pll and SRF5

DIOPT Version :9

Sequence 1:	NP_001263008.1	Gene:	pll / 43283	FlyBaseID:	FBgn0010441	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_178019.2	Gene:	SRF5 / 844238	AraportID:	AT1G78980	Length:	699	Species:	Arabidopsis thaliana

Alignment Length:	617	Identity:	151/617 - (24%)
Similarity:	229/617 - (37%)	Gaps:	204/617 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 AQNQANGNRTRSRSHLDNTMAIRL------LPLPVRAQLCAHLDALDV------------WQQLA 59
            ::|:.:||...|.|.:.|..:|.|      ..||...|..:.|:.||.            :..|.
plant   122 SENELDGNVPYSLSQMKNLQSINLGQNKLNGELPDMFQKLSKLETLDFSLNKLSGKLPQSFANLT 186

  Fly    60 TAVKLY--------------------------------PDQVEQISSQKQRGRSASNEFLNIW-- 90
            :..||:                                |::::.|.|....|        |.|
plant   187 SLKKLHLQDNRFTGDINVLRNLAIDDLNVEDNQFEGWIPNELKDIDSLLTGG--------NDWST 243

  Fly    91 --------GGQYNH----------------------------TVQTLFALFKKLKLHNAMRLIKD 119
                    |.:|..                            .:..|.||..|.|    ..|...
plant   244 ETAPPPPPGVKYGRKSSGSKDGGGITAGTGMVIAGACLGVLVLIIVLIALVSKKK----SSLSPH 304

  Fly   120 YVSEDLHKYIPR-----SVPTISELRAAPDSSAKVNNGPPFPS---------SSGVSNSNNNRT- 169
            ::.||...:.|:     |..:..|||.  |......:|....|         |.|:.:..::|.
plant   305 FIDEDNSHHTPKFKSLTSHGSAQELRV--DFGNDYKDGKSGDSGDENIHRIGSKGLKHYVSSRVM 367

  Fly   170 STTATEEIPSLESLGNIHISTVQRAAESLLEIDYAELENATDGWSPDNRLGQGGFGDVYRGKWKQ 234
            |.|.||....|    |...:|..|:|   :|.:.::|::||..:||.|.||:|..|.|||.|:..
plant   368 SFTDTEFANKL----NAKRTTSTRSA---VEFELSDLQSATANFSPGNLLGEGSIGRVYRAKYSD 425

  Fly   235 -LDVAIKVMNYRSPNIDQKMVELQQSYN---ELKYLNSIRHDNILALYGYSIKGGKPCLVYQLMK 295
             ..:|:|       .||..:.:..:|..   .:..|:.|||.||..|.||..:.|...|||:..:
plant   426 GRTLAVK-------KIDSTLFDSGKSEGITPIVMSLSKIRHQNIAELVGYCSEQGHNMLVYEYFR 483

  Fly   296 GGSLEARLRAHKAQNPLPALTWQQRFSISLGTARGIYFLHTARGTPLIHGDIKPANILLDQCLQP 360
            .|||...|  |.:......|||..|..|:|||||.:.:||.|....::|.:||.:|||||..|.|
plant   484 NGSLHEFL--HLSDCFSKPLTWNTRVRIALGTARAVEYLHEACSPSVMHKNIKSSNILLDADLNP 546

  Fly   361 KIGDFGLVREGPKSLDAVVEVNKVFGTKIYL-----------PPEFRNFRQLSTGVDVYSFGIVL 414
            ::.|:||                   :|.||           .||.|:....:...||||||:|:
plant   547 RLSDYGL-------------------SKFYLRTSQNLGEGYNAPEARDPSAYTPKSDVYSFGVVM 592

  Fly   415 LEVFTGRQVTD-RVPENETKKNLLDYVKQQWRQNRMELLEKHLAAPMGKELDMCMCAIEAGLH-- 476
            ||:.|||...| ..|..|  ::|:     :|            |.|...::|......:..||
plant   593 LELLTGRVPFDGEKPRPE--RSLV-----RW------------ATPQLHDIDALSNIADPALHGL 638

  Fly   477 ---------------CTALDPQDRPSMNAVLK 493
                           |..::|:.||.|:.|::
plant   639 YPPKSLSRFADIIALCVQVEPEFRPPMSEVVE 670

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_001263008.1	Death_Pelle	32..128	CDD:260021	27/183 (15%)
		STKc_IRAK	219..498	CDD:270968	91/308 (30%)
		TyrKc	219..495	CDD:197581	91/308 (30%)
SRF5	NP_178019.2	LRRNT_2	25..65	CDD:369783
		leucine-rich repeat	70..93	CDD:275380
		PLN00113	<73..680	CDD:215061	151/617 (24%)
		leucine-rich repeat	94..115	CDD:275380
		leucine-rich repeat	116..139	CDD:275380	5/16 (31%)
		leucine-rich repeat	140..163	CDD:275380	5/22 (23%)
		leucine-rich repeat	164..187	CDD:275380	4/22 (18%)
		leucine-rich repeat	188..209	CDD:275380	2/20 (10%)
		leucine-rich repeat	210..230	CDD:275380	1/19 (5%)
		PKc_like	410..675	CDD:389743	91/308 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.960