DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pll and AT1G51910

DIOPT Version :9

Sequence 1:	NP_001263008.1	Gene:	pll / 43283	FlyBaseID:	FBgn0010441	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_175603.2	Gene:	AT1G51910 / 841618	AraportID:	AT1G51910	Length:	876	Species:	Arabidopsis thaliana

Alignment Length:	526	Identity:	138/526 - (26%)
Similarity:	221/526 - (42%)	Gaps:	118/526 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 LDALDVWQQLAT-AVKLYPDQVEQISSQKQ----------RGRSASNEFLNIWGGQYNHTVQTLF 102
            ::||:|:..:.. .::.|.|:|..:.:.|:          :|...|.:... |.|.....:.:..
plant   347 INALEVYTLVENLLLETYQDEVSAMMNIKKTYGLSKKISWQGDPCSPQIYR-WEGLNCLYLDSDQ 410

  Fly   103 ALFKKLKL----------HNAMRLIK----DYVSEDLHKYIP-----RSVPTISELR-------A 141
            .|...|.|          |:...||:    |....||...||     ..:.|:..|:       .
plant   411 PLITSLNLRTSGLTGIITHDISNLIQLRELDLSDNDLSGEIPDFLADMKMLTLVNLKGNPKLNLT 475

  Fly   142 APDS-SAKVNN----------------GPPFP------SSSGV---------------SNSNNNR 168
            .||| ..::||                |..||      |.:||               ....:..
plant   476 VPDSIKHRINNKSLKLIIDENQSSEKHGIKFPLVAILASVAGVIALLAIFTICVIFKREKQGSGE 540

  Fly   169 TSTTATEEI-PSLESLGNIHISTVQRAAESLLEIDYAELENATDGWSPDNRLGQGGFGDVYRGKW 232
            ..|....|| .|.:|     |.|..|      :..|:|:...|:.:  :..||:||:|.||.||.
plant   541 APTRVNTEIRSSYQS-----IETKDR------KFTYSEILKMTNNF--ERVLGKGGYGRVYYGKL 592

  Fly   233 KQLDVAIKVMNYRSPNIDQKMVELQQSYNELKYLNSIRHDNILALYGYSIKGGKPCLVYQLMKGG 297
            ...:||:|::.:.|...|.|..:.     |::.|..:.|.:::.|.||...|....|:|:.|..|
plant   593 DDTEVAVKMLFHSSAEQDYKHFKA-----EVELLLRVHHRHLVGLVGYCDDGDNFALIYEYMANG 652

  Fly   298 SLEARLRAHKAQNPLPALTWQQRFSISLGTARGIYFLHTARGTPLIHGDIKPANILLDQCLQPKI 362
            .|:..:..:::.:   .|:|:.|..|::..|:|:.:||.....|::|.|:|..||||::..|.|:
plant   653 DLKENMSGNRSGH---VLSWENRMQIAMEAAQGLEYLHNGSRPPMVHRDVKTTNILLNELYQAKL 714

  Fly   363 GDFGLVREGPKSLDAVVEVNKVFGTKIYLPPEFRNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRV 427
            .||||.|..|...::.|. ..|.||..||.||   ...||...||||||:||||:.|.:.|.|..
plant   715 ADFGLSRSSPVDGESYVS-TIVAGTPGYLDPE---TNLLSEKTDVYSFGVVLLEIITNQPVIDTT 775

  Fly   428 PENETKKNLLDYVKQQWRQNRMELLE---KHLAAP-MGKELDM--CMCAIEAGLHCTALDPQDRP 486
            .|   |.::.|:|       ..:|:|   :::..| :.||.|.  ...|:|..|.|.......||
plant   776 RE---KAHITDWV-------GFKLMEGDIRNIIDPKLIKEFDTNGVWKAVELALSCVNPTSNHRP 830

  Fly   487 SMNAVL 492
            :|..|:
plant   831 TMPHVV 836

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_001263008.1	Death_Pelle	32..128	CDD:260021	20/103 (19%)
		STKc_IRAK	219..498	CDD:270968	92/280 (33%)
		TyrKc	219..495	CDD:197581	92/280 (33%)
AT1G51910	NP_175603.2	Malectin_like	32..354	CDD:289580	3/6 (50%)
		leucine-rich repeat	414..436	CDD:275380	4/21 (19%)
		leucine-rich repeat	437..460	CDD:275380	5/22 (23%)
		leucine-rich repeat	461..488	CDD:275380	7/26 (27%)
		TyrKc	575..843	CDD:197581	92/286 (32%)
		STKc_IRAK	579..841	CDD:270968	92/280 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.960