DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pll and AT1G51820

DIOPT Version :9

Sequence 1:	NP_001263008.1	Gene:	pll / 43283	FlyBaseID:	FBgn0010441	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_175594.2	Gene:	AT1G51820 / 841609	AraportID:	AT1G51820	Length:	885	Species:	Arabidopsis thaliana

Alignment Length:	505	Identity:	131/505 - (25%)
Similarity:	203/505 - (40%)	Gaps:	122/505 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 TMAIRLLPLPVRAQLCAHLDALDVWQQLATAVKLYPDQVEQISSQKQRGRSASN----------- 84
            |.||:.|         .||..||:.....|..  .|:.:..|.|......|.:|
plant   419 TQAIKNL---------THLQILDLSDNNLTGE--VPEFLADIKSLLVINLSGNNLSGSVPPSLLQ 472

  Fly    85 ---EFLNIWGGQYNHTVQTLFALFKKLKLHNAMRLIKDYVSEDLHKYIPRSVPTISELRA----- 141
               ..||:.|..  |.:.|..:..||              .||.||.....||.::.:.:
plant   473 KKGMKLNVEGNP--HILCTTGSCVKK--------------KEDGHKKKSVIVPVVASIASIAVLI 521

  Fly   142 ---------APDSSAKVNNGPPFPSSSGVSNSNNNRTSTTATEEIPSLESLGNIHISTVQRAAES 197
                     ....|.|| .||| ||....|:....|:|..|              |.|..|
plant   522 GALVLFLILRKKRSPKV-EGPP-PSYMQASDGRLPRSSEPA--------------IVTKNR---- 566

  Fly   198 LLEIDYAELENATDGWSPDNRLGQGGFGDVYRGKWKQLD-VAIKVMNYRSPNIDQKMVELQQSYN 261
              ...|:::...|:.:  ...||:||||.||.|.....: ||:|::::.|          .|.|.
plant   567 --RFSYSQVVIMTNNF--QRILGKGGFGMVYHGFVNGTEQVAVKILSHSS----------SQGYK 617

  Fly   262 ----ELKYLNSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPALTWQQRFS 322
                |::.|..:.|.|::.|.||..:|....|:|:.|..|.|:..:...:.:.   .|.|..|..
plant   618 QFKAEVELLLRVHHKNLVGLVGYCDEGDNLALIYEYMANGDLKEHMSGTRNRF---ILNWGTRLK 679

  Fly   323 ISLGTARGIYFLHTARGTPLIHGDIKPANILLDQCLQPKIGDFGLVR----EGPKSLDAVVEVNK 383
            |.:.:|:|:.:||.....|::|.|:|..||||::..:.|:.||||.|    ||...:..||.
plant   680 IVIESAQGLEYLHNGCKPPMVHRDVKTTNILLNEHFEAKLADFGLSRSFLIEGETHVSTVVA--- 741

  Fly   384 VFGTKIYLPPEFRNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQNR 448
              ||..||.||:.....|:...|||||||:|||:.|.|.|.|   ::..|.::.::|.....:..
plant   742 --GTPGYLDPEYHRTNWLTEKSDVYSFGILLLEIITNRHVID---QSREKPHIGEWVGVMLTKGD 801

  Fly   449 ME------LLEKHLAAPMGKELDMCMCAIEAGLHCTALDPQDRPSMNAVL 492
            ::      |.|.:.:..:.|       |:|..:.|.......||:|:.|:
plant   802 IQSIMDPSLNEDYDSGSVWK-------AVELAMSCLNHSSARRPTMSQVV 844

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_001263008.1	Death_Pelle	32..128	CDD:260021	23/109 (21%)
		STKc_IRAK	219..498	CDD:270968	87/289 (30%)
		TyrKc	219..495	CDD:197581	87/289 (30%)
AT1G51820	NP_175594.2	Malectin_like	29..345	CDD:289580
		LRR_8	405..462	CDD:290566	13/53 (25%)
		leucine-rich repeat	405..427	CDD:275380	4/16 (25%)
		leucine-rich repeat	428..451	CDD:275380	6/24 (25%)
		leucine-rich repeat	452..468	CDD:275380	2/15 (13%)
		TyrKc	580..847	CDD:197581	87/295 (29%)
		STKc_IRAK	584..849	CDD:270968	87/289 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.960