DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pll and PERK10

DIOPT Version :9

Sequence 1:	NP_001263008.1	Gene:	pll / 43283	FlyBaseID:	FBgn0010441	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_173940.2	Gene:	PERK10 / 839156	AraportID:	AT1G26150	Length:	762	Species:	Arabidopsis thaliana

Alignment Length:	379	Identity:	113/379 - (29%)
Similarity:	172/379 - (45%)	Gaps:	57/379 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 VPTISELRAAPDSSA--KVNNGPPFPSSSGVSNSNNNRTSTTATEEIPSLESLGNIHISTVQRAA 195
            :||..|..:....||  |..:..|.     |.|.::|||..:.:|.       |..        .
plant   368 MPTPMESSSPRSDSALLKTQSSAPL-----VGNRSSNRTYLSQSEP-------GGF--------G 412

  Fly   196 ESLLEIDYAELENATDGWSPDNRLGQGGFGDVYRGKW-KQLDVAIKVMNYRSPNIDQKMVELQQS 259
            :|.....|.||..||:|:|.:|.||:||||.||:|.. .:..||:|.:.......|::...
plant   413 QSRELFSYEELVIATNGFSDENLLGEGGFGRVYKGVLPDERVVAVKQLKIGGGQGDREFKA---- 473

  Fly   260 YNELKYLNSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPALTWQQRFSIS 324
              |:..::.:.|.|:|::.||.|...:..|:|..:...:|...|.|...    |.|.|..|..|:
plant   474 --EVDTISRVHHRNLLSMVGYCISENRRLLIYDYVPNNNLYFHLHAAGT----PGLDWATRVKIA 532

  Fly   325 LGTARGIYFLHTARGTPLIHGDIKPANILLDQCLQPKIGDFGLVREGPKSLDAVVEV-NKVFGTK 388
            .|.|||:.:||......:||.|||.:||||:......:.||||.:   .:||....: .:|.||.
plant   533 AGAARGLAYLHEDCHPRIIHRDIKSSNILLENNFHALVSDFGLAK---LALDCNTHITTRVMGTF 594

  Fly   389 IYLPPEFRNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQ----NRM 449
            .|:.||:.:..:|:...||:|||:||||:.|||:..|      ..:.|.|....:|.:    |..
plant   595 GYMAPEYASSGKLTEKSDVFSFGVVLLELITGRKPVD------ASQPLGDESLVEWARPLLSNAT 653

  Fly   450 ELLE-KHLAAP------MGKELDMCMCAIEAGLHCTALDPQDRPSMNAVLKRFE 496
            |..| ..||.|      :|.|:   ...|||...|.......||.|:.:::.|:
plant   654 ETEEFTALADPKLGRNYVGVEM---FRMIEAAAACIRHSATKRPRMSQIVRAFD 704

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_001263008.1	Death_Pelle	32..128	CDD:260021
		STKc_IRAK	219..498	CDD:270968	90/291 (31%)
		TyrKc	219..495	CDD:197581	89/288 (31%)
PERK10	NP_173940.2	STKc_IRAK	436..706	CDD:270968	90/291 (31%)
PERK10	NP_173940.2	STYKc	436..703	CDD:214568	89/288 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.870