DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pll and AT1G24650

DIOPT Version :9

Sequence 1:	NP_001263008.1	Gene:	pll / 43283	FlyBaseID:	FBgn0010441	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_173869.1	Gene:	AT1G24650 / 839079	AraportID:	AT1G24650	Length:	886	Species:	Arabidopsis thaliana

Alignment Length:	500	Identity:	143/500 - (28%)
Similarity:	223/500 - (44%)	Gaps:	95/500 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 AQNQANGNRTRSRSHLDNTMAIRLLPLPV-RAQLCAHLDALDVWQQLATAVKLYPDQVEQISSQK 76
            :||..||...:..:.|.|     |..|.| :.:||..:...:.  .:......:.|     ....
plant   396 SQNNLNGTIPQELAKLSN-----LKTLDVSKNRLCGEVPRFNT--TIVNTTGNFED-----CPNG 448

  Fly    77 QRGRSASNEFLNIWGGQYNHTVQTL------FALFKKLKLHNAMRLIKDYVSEDLHKYIPRSVPT 135
            ..|:.||:....|.|......:..|      |.|.||...::.|...:....:|..|.      |
plant   449 NAGKKASSNAGKIVGSVIGILLALLLIGVAIFFLVKKKMQYHKMHPQQQSSDQDAFKI------T 507

  Fly   136 ISELRAAPDSSAKVNNGPPFPSSSGVSNSNNNRTSTTATEEIPSLESLGNIHISTVQRAAESLLE 200
            |..|                  .:|||.|..:....       .|...|||.||         ::
plant   508 IENL------------------CTGVSESGFSGNDA-------HLGEAGNIVIS---------IQ 538

  Fly   201 IDYAELENATDGWSPDNRLGQGGFGDVYRGKWKQ-LDVAIKVMNYRSPNIDQKMVELQQSYNELK 264
            :    |.:||..:...|.||:||||.||:|:... ..:|:|.|  .|..|..|  .|.:..:|:.
plant   539 V----LRDATYNFDEKNILGRGGFGIVYKGELHDGTKIAVKRM--ESSIISGK--GLDEFKSEIA 595

  Fly   265 YLNSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPALTWQQRFSISLGTAR 329
            .|..:||.|::.|:||.::|.:..||||.|..|:|...:...|.:...| |.|.:|..|:|..||
plant   596 VLTRVRHRNLVVLHGYCLEGNERLLVYQYMPQGTLSRHIFYWKEEGLRP-LEWTRRLIIALDVAR 659

  Fly   330 GIYFLHTARGTPLIHGDIKPANILLDQCLQPKIGDFGLVR---EGPKSLDAVVEVNKVFGTKIYL 391
            |:.:|||......||.|:||:||||...:..|:.||||||   ||.:|::     .|:.||..||
plant   660 GVEYLHTLAHQSFIHRDLKPSNILLGDDMHAKVADFGLVRLAPEGTQSIE-----TKIAGTFGYL 719

  Fly   392 PPEFRNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQW---------RQN 447
            .||:....:::|.|||||||::|:|:.|||:..| |..:|.:.:|..:.::.:         ...
plant   720 APEYAVTGRVTTKVDVYSFGVILMELLTGRKALD-VARSEEEVHLATWFRRMFINKGSFPKAIDE 783

  Fly   448 RMELLEKHLAAPMGKELDMCMCAIEAGLHCTALDPQDRPSMNAVL 492
            .||:.|:.|     :.:::   ..|....|::.:|:|||.||.|:
plant   784 AMEVNEETL-----RSINI---VAELANQCSSREPRDRPDMNHVV 820

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_001263008.1	Death_Pelle	32..128	CDD:260021	18/102 (18%)
		STKc_IRAK	219..498	CDD:270968	101/286 (35%)
		TyrKc	219..495	CDD:197581	101/286 (35%)
AT1G24650	NP_173869.1	leucine-rich repeat	86..108	CDD:275380
		leucine-rich repeat	109..132	CDD:275380
		leucine-rich repeat	133..157	CDD:275380
		leucine-rich repeat	158..184	CDD:275380
		leucine-rich repeat	185..207	CDD:275380
		leucine-rich repeat	208..234	CDD:275380
		leucine-rich repeat	235..257	CDD:275380
		leucine-rich repeat	258..281	CDD:275380
		leucine-rich repeat	390..413	CDD:275380	5/16 (31%)
		S_TKc	547..>749	CDD:214567	83/211 (39%)
		STKc_IRAK	553..817	CDD:270968	98/282 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.870