DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pll and PERK8

DIOPT Version :9

Sequence 1:	NP_001263008.1	Gene:	pll / 43283	FlyBaseID:	FBgn0010441	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_198672.1	Gene:	PERK8 / 833844	AraportID:	AT5G38560	Length:	681	Species:	Arabidopsis thaliana

Alignment Length:	308	Identity:	95/308 - (30%)
Similarity:	147/308 - (47%)	Gaps:	35/308 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 YAELENATDGWSPDNRLGQGGFGDVYRGKWKQ-LDVAIKVMNYRSPNIDQKMVELQQSYNELKYL 266
            |.||...|.|:|..|.||:||||.||:|.... .:||:|.:.......:::...      |::.:
plant   329 YDELSQVTSGFSEKNLLGEGGFGCVYKGVLSDGREVAVKQLKIGGSQGEREFKA------EVEII 387

  Fly   267 NSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPALTWQQRFSISLGTARGI 331
            :.:.|.:::.|.||.|......|||..:...:|...|.|...    |.:||:.|..::.|.||||
plant   388 SRVHHRHLVTLVGYCISEQHRLLVYDYVPNNTLHYHLHAPGR----PVMTWETRVRVAAGAARGI 448

  Fly   332 YFLHTARGTPLIHGDIKPANILLDQCLQPKIGDFGLVREGPKSLDAVVEVN-KVFGTKIYLPPEF 395
            .:||......:||.|||.:|||||...:..:.||||.:.. :.||....|: :|.||..|:.||:
plant   449 AYLHEDCHPRIIHRDIKSSNILLDNSFEALVADFGLAKIA-QELDLNTHVSTRVMGTFGYMAPEY 512

  Fly   396 RNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQNRM----------E 450
            ....:||...||||:|::|||:.|||:..|      |.:.|.|....:|.:..:          |
plant   513 ATSGKLSEKADVYSYGVILLELITGRKPVD------TSQPLGDESLVEWARPLLGQAIENEEFDE 571

  Fly   451 LLEKHLAAPM--GKELDMCMCAIEAGLHCTALDPQDRPSMNAVLKRFE 496
            |::..|....  |:...|    :||...|.......||.|:.|::..:
plant   572 LVDPRLGKNFIPGEMFRM----VEAAAACVRHSAAKRPKMSQVVRALD 615

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_001263008.1	Death_Pelle	32..128	CDD:260021
		STKc_IRAK	219..498	CDD:270968	88/292 (30%)
		TyrKc	219..495	CDD:197581	88/289 (30%)
PERK8	NP_198672.1	STKc_IRAK	345..617	CDD:270968	88/292 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.870