DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pll and CRK14

DIOPT Version :9

Sequence 1:	NP_001263008.1	Gene:	pll / 43283	FlyBaseID:	FBgn0010441	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_567680.5	Gene:	CRK14 / 828421	AraportID:	AT4G23220	Length:	658	Species:	Arabidopsis thaliana

Alignment Length:	508	Identity:	138/508 - (27%)
Similarity:	227/508 - (44%)	Gaps:	107/508 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LCAHLDALD-VWQQLA---TAVKLYPDQVEQISSQKQRGRSASNEFLNIWGGQYNHTVQTLFALF 105
            :.::|...| ||::||   .|....|       |.|::..:|....|..:        |.::||
plant   143 ITSNLTEFDQVWEELARRMIASTTSP-------SSKRKYYAADVAALTAF--------QIIYAL- 191

  Fly   106 KKLKLHNAMRLIKDYVSEDLHKYIPRSVPTIS--------------------ELRAAPDSSAKVN 150
                    |:...|...||.|..:.:||....                    ||....::.::::
plant   192 --------MQCTPDLSLEDCHICLRQSVGDYETCCNGKQGGIVYRASCVFRWELFPFSEAFSRIS 248

  Fly   151 NGPP-----FPSSSGVSNSNNNRTSTTATEE------IPS-------LESLGNIHISTVQRAAES 197
            ..||     ||:...|:|:...:.|.|.:..      ||:       |.:||.:    |.|..:|
plant   249 LAPPPQSPAFPTLPAVTNTATKKGSITISIGIVWAIIIPTVIVVFLVLLALGFV----VYRRRKS 309

  Fly   198 L------------LEIDYAELENATDGWSPDNRLGQGGFGDVYRGKWKQLDVAIKVMNYRSPNID 250
            .            |:.|:..:|:||:.:|..|.:|:||||:|:.|.....:||||.::..|..
plant   310 YQGSSTDITITHSLQFDFKAIEDATNKFSESNIIGRGGFGEVFMGVLNGTEVAIKRLSKASRQ-- 372

  Fly   251 QKMVELQQSYNELKYLNSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPAL 315
                ..::..||:..:..:.|.|::.|.|:.::|.:..|||:.:...||:..|.....|.   .|
plant   373 ----GAREFKNEVVVVAKLHHRNLVKLLGFCLEGEEKILVYEFVPNKSLDYFLFDPTKQG---QL 430

  Fly   316 TWQQRFSISLGTARGIYFLHTARGTPLIHGDIKPANILLDQCLQPKIGDFGLVR------EGPKS 374
            .|.:|::|..|..|||.:||......:||.|:|.:|||||..:.|||.|||:.|      .|
plant   431 DWTKRYNIIRGITRGILYLHQDSRLTIIHRDLKASNILLDADMNPKIADFGMARIFGIDQSG--- 492

  Fly   375 LDAVVEVNKVFGTKIYLPPEFRNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDY 439
                ....|:.||:.|:|||:....|.||..||||||:::||:..||........:.|.:||:.|
plant   493 ----ANTKKIAGTRGYMPPEYVRQGQFSTRSDVYSFGVLVLEIICGRNNRFIHQSDTTVENLVTY 553

  Fly   440 VKQQWRQNR-MELLEKHLAAPMGKELDMCMCAIEAGLHCTALDPQDRPSMNAV 491
            ..:.||.:. :||::..::.....| ::..| |...|.|...:|.||||::.:
plant   554 AWRLWRNDSPLELVDPTISENCETE-EVTRC-IHIALLCVQHNPTDRPSLSTI 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_001263008.1	Death_Pelle	32..128	CDD:260021	20/86 (23%)
		STKc_IRAK	219..498	CDD:270968	91/280 (33%)
		TyrKc	219..495	CDD:197581	91/280 (33%)
CRK14	NP_567680.5	Stress-antifung	25..121	CDD:279926
		Stress-antifung	148..236	CDD:279926	21/111 (19%)
		TyrKc	342..604	CDD:197581	91/279 (33%)
		STKc_IRAK	343..608	CDD:270968	91/280 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910