DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pll and CRK37

DIOPT Version :9

Sequence 1:	NP_001263008.1	Gene:	pll / 43283	FlyBaseID:	FBgn0010441	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_192359.1	Gene:	CRK37 / 825780	AraportID:	AT4G04500	Length:	646	Species:	Arabidopsis thaliana

Alignment Length:	410	Identity:	121/410 - (29%)
Similarity:	195/410 - (47%)	Gaps:	57/410 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 YVSEDLHKYIPRSVPTISELRAAPDSSAKVNNGPPFPSSSGVSNSNNNRT---STTATEEIPSLE 181
            |...||:.|.           .|.|:..:|...||..||:.:....:.::   |..|...:||:.
plant   244 YFRWDLYPYY-----------RAFDNVVRVPAPPPQASSTIIDYGRDEKSFQGSNIAIIVVPSVI 297

  Fly   182 SL--------------GNIHISTV--QRAAESLLEIDYAELENATDGWSPDNRLGQGGFGDVYRG 230
            :|              .:..|:.|  ....:|:|..|...:..||:.:|.:|:|||||||.||:|
plant   298 NLIIFVVLIFSWKRKQSHTIINDVFDSNNGQSMLRFDLRMIVTATNNFSLENKLGQGGFGSVYKG 362

  Fly   231 KWKQ-LDVAIKVMNYRSPNIDQKMVELQQSYNELKYLNSIRHDNILALYGYSIKGGKPCLVYQLM 294
            .... .::|:|.:...|   .|..:|.:   ||:..|..::|.|::.|.|:..:..:..|||:.:
plant   363 ILPSGQEIAVKRLRKGS---GQGGMEFK---NEVLLLTRLQHRNLVKLLGFCNEKDEEILVYEFV 421

  Fly   295 KGGSLEARLRAHKAQNPLPALTWQQRFSISLGTARGIYFLHTARGTPLIHGDIKPANILLDQCLQ 359
            ...||:..:...:.:.   .|||..|::|..|.|||:.:||......:||.|:|.:|||||..:.
plant   422 PNSSLDHFIFDEEKRR---VLTWDVRYTIIEGVARGLLYLHEDSQLRIIHRDLKASNILLDAEMN 483

  Fly   360 PKIGDFGLVR-------EGPKSLDAVVEVNKVFGTKIYLPPEFRNFRQLSTGVDVYSFGIVLLEV 417
            ||:.|||:.|       .|        :.::|.||..|:.||:..:.|.||..||||||::|||:
plant   484 PKVADFGMARLFDMDETRG--------QTSRVVGTYGYMAPEYATYGQFSTKSDVYSFGVMLLEM 540

  Fly   418 FTGRQVTD-RVPENETKKNLLDYVKQQWRQNRMELLEKHLAAPMGK-ELDMCMCAIEAGLHCTAL 480
            .:|:.... ...|.|.::.|..:|.::|.:.|...:...||||... .::..|..|..||.|...
plant   541 ISGKSNKKLEKEEEEEEEELPAFVWKRWIEGRFAEIIDPLAAPSNNISINEVMKLIHIGLLCVQE 605

  Fly   481 DPQDRPSMNAVLKRFEPFVT 500
            |...|||:|::|...|...|
plant   606 DISKRPSINSILFWLERHAT 625

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_001263008.1	Death_Pelle	32..128	CDD:260021	3/7 (43%)
		STKc_IRAK	219..498	CDD:270968	95/288 (33%)
		TyrKc	219..495	CDD:197581	94/285 (33%)
CRK37	NP_192359.1	Stress-antifung	29..127	CDD:279926
		Stress-antifung	168..248	CDD:279926	1/3 (33%)
		Pkinase	345..617	CDD:278497	95/288 (33%)
		STKc_IRAK	351..622	CDD:270968	94/287 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910