DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pll and AT3G21340

DIOPT Version :9

Sequence 1:	NP_001263008.1	Gene:	pll / 43283	FlyBaseID:	FBgn0010441	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_188771.2	Gene:	AT3G21340 / 821688	AraportID:	AT3G21340	Length:	899	Species:	Arabidopsis thaliana

Alignment Length:	514	Identity:	132/514 - (25%)
Similarity:	214/514 - (41%)	Gaps:	122/514 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SRSHLDNTMAIRLLPLPVRAQLCAHLDALDVWQQLATAVKLYPDQVEQISSQKQRGRSASNEFLN 88
            |.|||...:|..:       |...||..||:.....|..  .|:.:..|.|..         .:|
plant   422 SSSHLTGIIAQGI-------QNLTHLQELDLSNNNLTGG--IPEFLADIKSLL---------VIN 468

  Fly    89 IWGGQYNHTVQTLFALFKKLKL---HNAMRLIKDYVSEDLHKYIPRSVPTISELRAAPDSSAKVN 150
            :.|..:|.::..:....|.|||   .||..:..|.:..:               :|....:.|:|
plant   469 LSGNNFNGSIPQILLQKKGLKLILEGNANLICPDGLCVN---------------KAGNGGAKKMN 518

  Fly   151 NGPPFPSS-------------------SGVSNSNN-NRTSTTATEEIPSLESLGNIHISTVQRAA 195
            ...|..:|                   ...|||.: ..:|.|...|:.::            |::
plant   519 VVIPIVASVAFVVVLGSALAFFFIFKKKKTSNSQDLGPSSYTQVSEVRTI------------RSS 571

  Fly   196 ESLL-----EIDYAELENATDGWSPDNRLGQGGFGDVYRGKWKQLD-VAIKVMNYRSPNIDQKMV 254
            ||.:     ...|:|:...|:.:  :..||:||||.||.|.....: ||:|::::.|
plant   572 ESAIMTKNRRFTYSEVVTMTNNF--ERVLGKGGFGMVYHGTVNNTEQVAVKMLSHSS-------- 626

  Fly   255 ELQQSYNELK----YLNSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPAL 315
              .|.|.|.|    .|..:.|.|::.|.||..:|....|:|:.|..|.|...:...:..:   .|
plant   627 --SQGYKEFKAEVELLLRVHHKNLVGLVGYCDEGENLALIYEYMANGDLREHMSGKRGGS---IL 686

  Fly   316 TWQQRFSISLGTARGIYFLHTARGTPLIHGDIKPANILLDQCLQPKIGDFGLVR----EGPKSLD 376
            .|:.|..|.:.:|:|:.:||.....|::|.|:|..||||::.|..|:.||||.|    ||...:.
plant   687 NWETRLKIVVESAQGLEYLHNGCKPPMVHRDVKTTNILLNEHLHAKLADFGLSRSFPIEGETHVS 751

  Fly   377 AVVEVNKVFGTKIYLPPEFRNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVK 441
            .||.     ||..||.||:.....|:...|||||||||||:.|.:.|   :.::..|.::.::|.
plant   752 TVVA-----GTPGYLDPEYYRTNWLNEKSDVYSFGIVLLEIITNQLV---INQSREKPHIAEWVG 808

  Fly   442 QQWR----QNRME--LLEKHLAAPMGKELDMCMCAIEAGLHCTALDPQD--RPSMNAVL 492
            ....    ||.|:  |...:.:..:.:       |:|..:.|  |:|..  ||:|:.|:
plant   809 LMLTKGDIQNIMDPKLYGDYDSGSVWR-------AVELAMSC--LNPSSARRPTMSQVV 858

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_001263008.1	Death_Pelle	32..128	CDD:260021	20/98 (20%)
		STKc_IRAK	219..498	CDD:270968	91/291 (31%)
		TyrKc	219..495	CDD:197581	91/291 (31%)
AT3G21340	NP_188771.2	Malectin_like	36..357	CDD:289580
		LRR_8	416..474	CDD:290566	16/69 (23%)
		leucine-rich repeat	416..439	CDD:275380	6/23 (26%)
		leucine-rich repeat	440..463	CDD:275380	6/24 (25%)
		leucine-rich repeat	464..480	CDD:275380	3/24 (13%)
		TyrKc	594..861	CDD:197581	91/297 (31%)
		STKc_IRAK	598..863	CDD:270968	91/291 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.870