Protein Alignment pll and IKU2

DIOPT Version :10

• Sequence 1: NP_476971.1
• Gene: pll / 43283
• FlyBaseID: FBgn0010441
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_188604.1
• Gene: IKU2 / 821507
• AraportID: AT3G19700
• Length: 991
• Species: Arabidopsis thaliana
• Alignment Length: 478
• Identity: 111/478 - (23%)
• Similarity: 201/478 - (42%)
• Gaps: 122/478 - (25%)

  Fly   119 DYVSEDLHKYIPRSVPTISELRAAPDSSAKVNNGPPFPSSS---GVSNSNNNRTSTTATEEIPSL 180
            ::....|.:.||.|:.::..|.:...|..|::...|...|:   .:.:.:||:.:.:..|.:.|.
plant   514 NFAGNSLSEEIPESLGSLKLLNSLNLSGNKLSGMIPVGLSALKLSLLDLSNNQLTGSVPESLVSG 578

  Fly   181 ESLGNI-------------------------HIS------------------------------- 189
            ...||.                         |:|
plant   579 SFEGNSGLCSSKIRYLRPCPLGKPHSQGKRKHLSKVDMCFIVAAILALFFLFSYVIFKIRRDKLN 643

  Fly   190 -TVQR----AAESLLEIDYAELENATDGWSPDNRLGQGGFGDVYRGKWKQLD-VAIKVM------ 242
             |||:    ...|...:::.|:| ..|....:|.:|:||.|:||:...:..: :|:|.:
plant   644 KTVQKKNDWQVSSFRLLNFNEME-IIDEIKSENIIGRGGQGNVYKVSLRSGETLAVKHIWCPESS 707

  Fly   243 --------------NYRSPNIDQKMVELQQSYNELKYLNSIRHDNILALYGYSIKGGKPCLVYQL 293
                          |.||.|.:.:.        |:..|::|:|.|::.|:..........|||:.
plant   708 HESFRSSTAMLSDGNNRSNNGEFEA--------EVATLSNIKHINVVKLFCSITCEDSKLLVYEY 764

  Fly   294 MKGGSLEARLRAHKAQNPLPALTWQQRFSISLGTARGIYFLHTARGTPLIHGDIKPANILLDQCL 358
            |..|||..:|...:.:.   .:.|:.|.:::||.|:|:.:||.....|:||.|:|.:|||||:..
plant   765 MPNGSLWEQLHERRGEQ---EIGWRVRQALALGAAKGLEYLHHGLDRPVIHRDVKSSNILLDEEW 826

  Fly   359 QPKIGDFGLVREGPKSLDAVVEVNK---------VFGTKIYLPPEFRNFRQLSTGVDVYSFGIVL 414
            :|:|.||||.:        :::.:.         |.||..|:.||:....:::...||||||:||
plant   827 RPRIADFGLAK--------IIQADSVQRDFSAPLVKGTLGYIAPEYAYTTKVNEKSDVYSFGVVL 883

  Fly   415 LEVFTGRQ--VTDRVPENETKKNLLDYVKQQWRQNRMELLEKHLAAPMGKELDMCMCAIEAGLHC 477
            :|:.||::  .||....|:....:....|:..|:..|:|::..:.....::   .:..:...|.|
plant   884 MELVTGKKPLETDFGENNDIVMWVWSVSKETNREMMMKLIDTSIEDEYKED---ALKVLTIALLC 945

  Fly   478 TALDPQDRPSMNAV---LKRFEP 497
            |...||.||.|.:|   |::.||
plant   946 TDKSPQARPFMKSVVSMLEKIEP 968

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_476971.1	Death_Pelle	32..128	CDD:260021	1/8 (13%)
		STKc_IRAK	219..498	CDD:270968	86/314 (27%)
IKU2	NP_188604.1	PLN00113	4..964	CDD:215061	108/472 (23%)
		leucine-rich repeat	102..125	CDD:275380
		leucine-rich repeat	126..148	CDD:275380
		leucine-rich repeat	149..173	CDD:275380
		leucine-rich repeat	174..198	CDD:275380
		leucine-rich repeat	199..222	CDD:275380
		leucine-rich repeat	223..246	CDD:275380
		leucine-rich repeat	247..270	CDD:275380
		leucine-rich repeat	271..293	CDD:275380
		leucine-rich repeat	294..317	CDD:275380
		leucine-rich repeat	318..389	CDD:275380
		leucine-rich repeat	390..413	CDD:275380
		leucine-rich repeat	414..437	CDD:275380
		leucine-rich repeat	438..461	CDD:275380
		leucine-rich repeat	462..483	CDD:275380
		leucine-rich repeat	486..509	CDD:275380
		leucine-rich repeat	510..528	CDD:275380	3/13 (23%)
		leucine-rich repeat	555..577	CDD:275380	3/21 (14%)