DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pll and ANX1

DIOPT Version :9

Sequence 1:	NP_001263008.1	Gene:	pll / 43283	FlyBaseID:	FBgn0010441	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_187120.1	Gene:	ANX1 / 819627	AraportID:	AT3G04690	Length:	850	Species:	Arabidopsis thaliana

Alignment Length:	403	Identity:	121/403 - (30%)
Similarity:	198/403 - (49%)	Gaps:	59/403 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 KDYVSEDLHKYIPRSVPTISE--LRAAPDSSAKVNNGPPFPSSSGVSNSNN-----NRTSTTATE 175
            |::.:|..|.:|..|...:..  :.|...::.|...|    ...|.|::::     ..::|:.|:
plant   421 KEFKNEKRHAFIIGSAGGVLAVLIGALCFTAYKKKQG----YQGGDSHTSSWLPIYGNSTTSGTK 481

  Fly   176 EIPSLESLGNIHISTVQRAAESLLEIDYAELENATDGWSPDNRLGQGGFGDVYRGKWKQLD---- 236
            ...|.:|....|:|.:  ||.........|:::.|..:...|.:|.||||.||:|   .:|
plant   482 STISGKSNNGSHLSNL--AAGLCRRFSLPEIKHGTQNFDDSNVIGVGGFGKVYKG---VIDGTTK 541

  Fly   237 VAIKVMNYRSPNIDQKMVELQQSYNELKYLNSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEA 301
            ||:|..|   ||.:|.:.|.:   .|::.|:.:||.::::|.||..:||:.||||..|..|:
plant   542 VAVKKSN---PNSEQGLNEFE---TEIELLSRLRHKHLVSLIGYCDEGGEMCLVYDYMAFGT--- 597

  Fly   302 RLRAHKAQNPLPALTWQQRFSISLGTARGIYFLHTARGTPLIHGDIKPANILLDQCLQPKIGDFG 366
             ||.|......|.|||::|..|::|.|||:::|||.....:||.|:|..|||:|:....|:.|||
plant   598 -LREHLYNTKKPQLTWKRRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILVDENWVAKVSDFG 661

  Fly   367 LVREGPKSLDAVVE--VNKVFGTKIYLPPEFRNFRQLSTGVDVYSFGIVLLEVFTGR-QVTDRVP 428
            |.:.||......|.  |...||   ||.||:...:||:...||||||:||.|:...| .:...:|
plant   662 LSKTGPNMNGGHVTTVVKGSFG---YLDPEYFRRQQLTEKSDVYSFGVVLFEILCARPALNPSLP 723

  Fly   429 ENETKKNLLDYVKQQWRQNRME-LLEKHLAAPMGKELDMCM---------CAIEAGLHCTALDPQ 483
            :.:.  :|.|:.....|:..:| :::.:|...:..|   |:         |..::||
plant   724 KEQV--SLGDWAMNCKRKGNLEDIIDPNLKGKINAE---CLKKFADTAEKCLNDSGL-------- 775

  Fly   484 DRPSMNAVLKRFE 496
            :||:|..||...|
plant   776 ERPTMGDVLWNLE 788

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_001263008.1	Death_Pelle	32..128	CDD:260021	3/9 (33%)
		STKc_IRAK	219..498	CDD:270968	100/295 (34%)
		TyrKc	219..495	CDD:197581	99/292 (34%)
ANX1	NP_187120.1	Malectin	29..170	CDD:288557
		Malectin_like	31..396	CDD:289580
		Malectin	213..372	CDD:288557
		STYKc	522..784	CDD:214568	97/290 (33%)
		STKc_IRAK	523..788	CDD:270968	99/293 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.870