DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pll and AT2G28970

DIOPT Version :9

Sequence 1:	NP_001263008.1	Gene:	pll / 43283	FlyBaseID:	FBgn0010441	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_180463.1	Gene:	AT2G28970 / 817446	AraportID:	AT2G28970	Length:	786	Species:	Arabidopsis thaliana

Alignment Length:	484	Identity:	128/484 - (26%)
Similarity:	203/484 - (41%)	Gaps:	92/484 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LPVRAQLCAHLDALDVWQQLATAVKLYPDQVEQISSQKQRGRSASNEFLNIWGGQYNHTV-QTLF 102
            ||...|....:..||:.....|.  |.|..:..|.|.         ..|::.|..:..:| |||.
plant   324 LPSVFQNLTQIQELDLSNNSLTG--LVPSFLANIKSL---------SLLDLSGNNFTGSVPQTLL 377

  Fly   103 ALFKK---LKLHNAMRLIKDYVSEDLHKYIPRSVPTISEL-------------------RAAPDS 145
            ...|:   |||.....|.| :.|.:..|.....||.|:.:                   :...|:
plant   378 DREKEGLVLKLEGNPELCK-FSSCNPKKKKGLLVPVIASISSVLIVIVVVALFFVLRKKKMPSDA 441

  Fly   146 SAKVNNGPPFPSSSGVSNSNNNRTSTTATEEIPSLESLGNIHISTVQRAAESLLEIDYAELENAT 210
            .|     ||......|..:.::.:|..:.:                       :...|.|::..|
plant   442 QA-----PPSLPVEDVGQAKHSESSFVSKK-----------------------IRFAYFEVQEMT 478

  Fly   211 DGWSPDNRLGQGGFGDVYRG--KWKQLDVAIKVMNYRSPNIDQKMVELQQSYN----ELKYLNSI 269
            :.:  ...||:||||.||.|  ...| .||:|:::..|          .|.|.    |::.|..:
plant   479 NNF--QRVLGEGGFGVVYHGCVNGTQ-QVAVKLLSQSS----------SQGYKHFKAEVELLMRV 530

  Fly   270 RHDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPALTWQQRFSISLGTARGIYFL 334
            .|.|:::|.||..:|....|:|:.|..|.|:..|...:...   .|:|:.|..:::..|.|:.:|
plant   531 HHKNLVSLVGYCDEGDHLALIYEYMPNGDLKQHLSGKRGGF---VLSWESRLRVAVDAALGLEYL 592

  Fly   335 HTARGTPLIHGDIKPANILLDQCLQPKIGDFGLVREGPKSLDAVVEVNKVFGTKIYLPPEFRNFR 399
            ||....|::|.|||..|||||:..|.|:.||||.|..|...:..|. ..|.||..||.||:....
plant   593 HTGCKPPMVHRDIKSTNILLDERFQAKLADFGLSRSFPTENETHVS-TVVAGTPGYLDPEYYQTN 656

  Fly   400 QLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQNRM-ELLEKHLAAPMGKE 463
            .|:...|||||||||||:.|.|.:   :.::..|.:|:::|....|...: .:::.:|..  ..:
plant   657 WLTEKSDVYSFGIVLLEIITNRPI---IQQSREKPHLVEWVGFIVRTGDIGNIVDPNLHG--AYD 716

  Fly   464 LDMCMCAIEAGLHCTALDPQDRPSMNAVL 492
            :.....|||..:.|..:....||||:.|:
plant   717 VGSVWKAIELAMSCVNISSARRPSMSQVV 745

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_001263008.1	Death_Pelle	32..128	CDD:260021	23/92 (25%)
		STKc_IRAK	219..498	CDD:270968	92/281 (33%)
		TyrKc	219..495	CDD:197581	92/281 (33%)
AT2G28970	NP_180463.1	Malectin_like	28..251	CDD:289580
		LRR_8	312..368	CDD:290566	12/54 (22%)
		leucine-rich repeat	313..333	CDD:275380	3/8 (38%)
		leucine-rich repeat	334..357	CDD:275380	6/24 (25%)
		leucine-rich repeat	358..376	CDD:275380	4/26 (15%)
		Pkinase	483..746	CDD:278497	92/283 (33%)
		STKc_IRAK	485..750	CDD:270968	92/281 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.870