DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pll and RIPK

DIOPT Version :9

Sequence 1:	NP_001263008.1	Gene:	pll / 43283	FlyBaseID:	FBgn0010441	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_178651.1	Gene:	RIPK / 815147	AraportID:	AT2G05940	Length:	462	Species:	Arabidopsis thaliana

Alignment Length:	341	Identity:	107/341 - (31%)
Similarity:	170/341 - (49%)	Gaps:	45/341 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 NNRTSTTATEEIPSLESLGNIHISTVQRAAESLLEIDYAELENATDGWSPDNRLGQGGFGDVYRG 230
            :|.:|.|.:|::....:..::|:.|:            |||:..|..:|..|.||:||||.|::|
plant    52 SNPSSNTLSEDLSISLAGSDLHVFTL------------AELKVITQSFSSTNFLGEGGFGPVHKG 104

  Fly   231 --------KWKQLDVAIKVMNYRSPNIDQKMVELQ---QSYNELKYLNSIRHDNILALYGYSIKG 284
                    ..|...||:|:::...         ||   :...|:.:|..::|.|::.|.||..:.
plant   105 FIDDKLRPGLKAQPVAVKLLDLEG---------LQGHREWLTEVMFLGQLKHKNLVKLIGYCCEE 160

  Fly   285 GKPCLVYQLMKGGSLEARL-RAHKAQNPLPALTWQQRFSISLGTARGIYFLHTARGTPLIHGDIK 348
            ....|||:.|..||||.:| |.:.|     :|.|..|..|:.|.|.|:.|||.|. .|:|:.|.|
plant   161 EHRTLVYEFMPRGSLENQLFRRYSA-----SLPWSTRMKIAHGAATGLQFLHEAE-NPVIYRDFK 219

  Fly   349 PANILLDQCLQPKIGDFGLVREGPKSLDAVVEVNKVFGTKIYLPPEFRNFRQLSTGVDVYSFGIV 413
            .:|||||.....|:.||||.::||:..|..|. .:|.||:.|..||:.....|:...||||||:|
plant   220 ASNILLDSDYTAKLSDFGLAKDGPEGDDTHVS-TRVMGTQGYAAPEYIMTGHLTARSDVYSFGVV 283

  Fly   414 LLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQNR--MELLEKHLAAPMGKELDMCMCAIEAGLH 476
            |||:.|||:..|: ..:..::||:|:.:......|  ..:::..|.....:  .....|......
plant   284 LLELLTGRRSVDK-KRSSREQNLVDWARPMLNDPRKLSRIMDPRLEGQYSE--TGARKAATLAYQ 345

  Fly   477 CTALDPQDRPSMNAVL 492
            |.:..|::||.|:||:
plant   346 CLSHRPKNRPCMSAVV 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_001263008.1	Death_Pelle	32..128	CDD:260021
		STKc_IRAK	219..498	CDD:270968	95/288 (33%)
		TyrKc	219..495	CDD:197581	95/288 (33%)
RIPK	NP_178651.1	STKc_IRAK	93..367	CDD:270968	95/288 (33%)
RIPK	NP_178651.1	TyrKc	93..364	CDD:197581	95/288 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1620
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	3.010