Protein Alignment pll and irak4

DIOPT Version :10

• Sequence 1: NP_476971.1
• Gene: pll / 43283
• FlyBaseID: FBgn0010441
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001116877.1
• Gene: irak4 / 733738
• XenbaseID: XB-GENE-492219
• Length: 457
• Species: Xenopus tropicalis
• Alignment Length: 481
• Identity: 140/481 - (29%)
• Similarity: 220/481 - (45%)
• Gaps: 61/481 - (12%)

  Fly    34 IRLLPLPVRAQLCAHLDALDVWQQLATAVKLYPD--------QVEQISSQKQRGRSASNEFLNIW 90
            :|.|...:..||...||..:.|:::|..: :.|.        .:.:.....|.|:|.:.|.|..|
 Frog    11 VRNLSHGMHRQLADLLDPQEGWKKIAVNI-MKPSGDARYSQFHIRRFEGTVQMGKSPTCELLYDW 74

  Fly    91 GGQYNHTVQTLFALFKKLKLHNAMRLIKDYVSEDLHKYIPRSVPTISELRAAPDSSAKVNNGPPF 155
             |..|.|||.|..|.:|.....|..|:           :|............|.|||  .|.|..
 Frog    75 -GTTNCTVQDLKDLLQKNGFSAAASLL-----------LPAKNTENVNASTRPVSSA--INAPCE 125

  Fly   156 PSSSGVSNSNNNRTSTTATEEIPSLESLGNIHISTVQRAAESLLEIDYAELENATDGW------S 214
            .|::.|.::.|..|..:...|...::...::.|.          ...:.|::.:|:.:      .
 Frog   126 MSAAEVIDTCNPHTYQSKGPEENEVDDFDDMGIG----------RFSFTEVKQSTNNFDIRPVSE 180

  Fly   215 PDNRLGQGGFGDVYRGKWKQLDVAIKVMNYRSPNIDQKMVELQ-QSYNELKYLNSIRHDNILALY 278
            ..|:||:||||.|::|:.|:..||:|.:   :..:|..:.:|. |...|:|.:...:|:|::.|.
 Frog   181 GGNKLGEGGFGVVFKGEIKEKIVAVKKL---TELVDASIQDLTCQFEQEIKIMGKCQHENLVKLL 242

  Fly   279 GYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPALTWQQRFSISLGTARGIYFLHTARGTPLI 343
            |||..|.:.||:|..|..|||..||   ...|..|.::|..|.:|:.|||.||.:||.   ...:
 Frog   243 GYSKDGDQYCLIYTYMPNGSLLDRL---ACLNDTPPISWVLRCNIAYGTANGINYLHE---NSHV 301

  Fly   344 HGDIKPANILLDQCLQPKIGDFGLVR-EGPKSLDAVVEVNKVFGTKIYLPPE-FRNFRQLSTGVD 406
            |.|||.||||||..|.|||.||||.| .|..|...:.|  ::.||..|:.|| .|.  :::...|
 Frog   302 HRDIKSANILLDDTLVPKISDFGLSRATGQFSKTMMTE--RIVGTTAYMAPEALRG--EITIKSD 362

  Fly   407 VYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQNRMELLEKHLAAPMGK-ELDMCMCA 470
            ::|||:||||:.:|....|   ||.:...||| :|::..:.. :.:|::....||. |.:.....
 Frog   363 IFSFGVVLLEIISGLAPVD---ENRSPSLLLD-IKEEIEEEE-KTIEEYTDKKMGDVEPNTLKKM 422

  Fly   471 IEAGLHCTALDPQDRPSMNAVLKRFE 496
            ......|.......||.:..||:..|
 Frog   423 YTVASQCLNQMKNRRPVITRVLQNLE 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_476971.1	Death_Pelle	32..128	CDD:260021	25/101 (25%)
		STKc_IRAK	219..498	CDD:270968	99/282 (35%)
irak4	NP_001116877.1	Death_IRAK4	9..108	CDD:260060	26/109 (24%)
		STKc_IRAK4	163..450	CDD:271060	102/304 (34%)