Protein Alignment pll and irak2

DIOPT Version :10

• Sequence 1: NP_476971.1
• Gene: pll / 43283
• FlyBaseID: FBgn0010441
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_012816354.1
• Gene: irak2 / 493227
• XenbaseID: XB-GENE-876387
• Length: 666
• Species: Xenopus tropicalis
• Alignment Length: 522
• Identity: 137/522 - (26%)
• Similarity: 219/522 - (41%)
• Gaps: 113/522 - (21%)

  Fly    15 NQANGNRTRSRSHLDNTMAIRLLPLPVRAQLCAHLDALDVWQQLATAVKLYPDQ--VEQISSQKQ 77
            :|.||:..|          |..:|..:....|..:|.|..|:.:..|..:..||  :.:|.|.::
 Frog     4 SQHNGSSPR----------IFDIPAKIMDDFCRCMDCLSDWEWMRFASSVIDDQTVLRRIRSYEK 58

  Fly    78 RGRSASNEFLNIWGGQYNHTVQTLFALFKKLKLHNAMRLIKDYVSEDLHKYIPRSV--PTISELR 140
            .|.|.:.|.:..| ||...|:|.|....:||:::.|:.:        |.::.|.||  ..:.|.|
 Frog    59 TGVSVTRELMWSW-GQKLPTLQKLVERLQKLEMYRALGI--------LQQWSPLSVIASKVPERR 114

  Fly   141 -AAPDSSAKVNN--------------------GPPFPSSSGVSNSNNNRTSTT--ATEEIPSLES 182
             |..:|..|.:|                    .||.||....|.|..:..|.|  :.||:.|:..
 Frog   115 KAEKESDLKTDNKLPELTYTSPLELPTPPLPAPPPPPSDLLHSLSIQSECSLTCHSPEEVLSIPQ 179

  Fly   183 LGNIHISTVQRAAESLLEI-DYAELENATDGWSPDNRLGQGGFGDVYRGKWKQLDVAIKVMNYRS 246
            ......|      :.|.:| ...::|:|||.:.....:.:|.|.|||.|..:....|||    |.
 Frog   180 QEKSSFS------KGLCKIWTQKDVEDATDCFCSSKIIHEGEFADVYMGHKQDKLYAIK----RL 234

  Fly   247 PNIDQKMVELQQSYNELKYLNSIR--HDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQ 309
            ..:..:..:...|:...:...|.|  |.|||.|.|:.::|...||:.|.::.|||:..|:    |
 Frog   235 KKVQDEEQKRMSSFFHTEAQISFRCCHANILPLLGFCVEGDCSCLINQFIRNGSLDLALQ----Q 295

  Fly   310 NPLPALTWQQRFSISLGTARGIYFLHTARGTPLIHGDIKPANILLDQCLQPKIGDFGLVREGP-- 372
            :....|.|::|..|:||..:.|..||:   ..::||:||.:||.||:...||:|..|| |..|
 Frog   296 SGNHILNWERRLKIALGFLKAIRHLHS---NDILHGNIKSSNIFLDENSFPKLGHSGL-RFCPDK 356

  Fly   373 -------KSLDAVVEVNKVFGTKIYLPPEFRNFRQLSTGVDVYSFGIVLLEVFTGRQVTDR---- 426
                   ||.|..|.       :.|||..|....||:...|::|.|:||.|:.||::..|:
 Frog   357 QAGYTKAKSKDLQVH-------QPYLPDSFFRHGQLTVQTDIFSCGVVLAEILTGQKACDKSRNP 414

  Fly   427 -------VPENETKKNLLD-----------------YVKQQWRQNRMELLEKHLAAPMGKELDMC 467
                   :.|.|..|..||                 .:.:::..:|...|..:.|..:  .|..|
 Frog   415 VYLKDLFLEELERAKEYLDSDGKQADHESPESLCSHQISRKYIDSRAGFLSNNAAFQL--SLAAC 477

  Fly   468 MC 469
            :|
 Frog   478 LC 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_476971.1	Death_Pelle	32..128	CDD:260021	24/97 (25%)
		STKc_IRAK	219..498	CDD:270968	82/290 (28%)
irak2	XP_012816354.1	Death_IRAK2	11..98	CDD:176773	24/105 (23%)
		Protein Kinases, catalytic domain	211..502	CDD:473864	82/290 (28%)