DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pll and PERK14

DIOPT Version :9

Sequence 1:	NP_001263008.1	Gene:	pll / 43283	FlyBaseID:	FBgn0010441	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001320117.1	Gene:	PERK14 / 3770575	AraportID:	AT4G32710	Length:	731	Species:	Arabidopsis thaliana

Alignment Length:	380	Identity:	111/380 - (29%)
Similarity:	175/380 - (46%)	Gaps:	72/380 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 APDSSAKVNNGPP-----FPSSSGVSNSNNNRTSTTATEEIPSLESLGNIHISTVQRAAESLLEI 201
            |..:.|.|...||     :.||.|.....||  |......:||    |               ..
plant   334 AGTNQAHVITMPPPIHAKYISSGGCDTKENN--SVAKNISMPS----G---------------MF 377

  Fly   202 DYAELENATDGWSPDNRLGQGGFGDVYRGKWKQ-LDVAIKVMNYRSPNIDQKMVELQQSYNELKY 265
            .|.||..||.|:|.:|.||:||||.|::|..|. .:||:|.:...|...::   |.|.   |:..
plant   378 SYEELSKATGGFSEENLLGEGGFGYVHKGVLKNGTEVAVKQLKIGSYQGER---EFQA---EVDT 436

  Fly   266 LNSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPALTWQQRFSISLGTARG 330
            ::.:.|.::::|.||.:.|.|..|||:.:...:||..|..::..    .|.|:.|..|::|.|:|
plant   437 ISRVHHKHLVSLVGYCVNGDKRLLVYEFVPKDTLEFHLHENRGS----VLEWEMRLRIAVGAAKG 497

  Fly   331 IYFLHTARGTPLIHGDIKPANILLDQCLQPKIGDFGLVREGPKSLDAVVEVN-KVFGTKIYLPPE 394
            :.:||......:||.|||.||||||...:.|:.||||.:....:..:...:: :|.||..|:.||
plant   498 LAYLHEDCSPTIIHRDIKAANILLDSKFEAKVSDFGLAKFFSDTNSSFTHISTRVVGTFGYMAPE 562

  Fly   395 FRNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQNRMELLEKHLAAP 459
            :.:..:::...||||||:||||:.|||. :....::.|.::|:|:.:        .||.|.::
plant   563 YASSGKVTDKSDVYSFGVVLLELITGRP-SIFAKDSSTNQSLVDWAR--------PLLTKAIS-- 616

  Fly   460 MGKELD------------------MCMCAIEAGLHCTALDPQDRPSMNAVLKRFE 496
             |:..|                  |..||..    |.......||.|:.|::..|
plant   617 -GESFDFLVDSRLEKNYDTTQMANMAACAAA----CIRQSAWLRPRMSQVVRALE 666

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_001263008.1	Death_Pelle	32..128	CDD:260021
		STKc_IRAK	219..498	CDD:270968	89/298 (30%)
		TyrKc	219..495	CDD:197581	88/295 (30%)
PERK14	NP_001320117.1	STKc_IRAK	395..667	CDD:270968	89/298 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910