Protein Alignment pll and Irak1

DIOPT Version :10

• Sequence 1: NP_476971.1
• Gene: pll / 43283
• FlyBaseID: FBgn0010441
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_006229660.1
• Gene: Irak1 / 363520
• RGDID: 1563841
• Length: 711
• Species: Rattus norvegicus
• Alignment Length: 516
• Identity: 156/516 - (30%)
• Similarity: 219/516 - (42%)
• Gaps: 97/516 - (18%)

  Fly    49 LDALDV--WQQLATAVKLYPDQVEQISSQKQRGRSASNEFLNIWGGQYNHTVQTLFALFKKLKLH 111
            :|||:.  |.|.|..:  ..||.|....::...|:||  .|..|..: |..|..|..:...|:|.
  Rat    34 MDALEPADWCQFAALI--VRDQTELRLCERSEQRTAS--VLWPWINR-NARVADLVHILTHLQLL 93

  Fly   112 NAMRLIKDYVSEDLHKYIPRSV-------PTISELRAAPD----------SSAKVNNGPPFPSSS 159
            .|..:|..:       :.|.||       |..|.:.|..:          |||.....|.||.|.
  Rat    94 RARDIITAW-------HPPASVLPPSTGAPRPSSISAGSETEDWSPRKLQSSASTFLSPAFPGSQ 151

  Fly   160 GVSNSNNNRTSTTATEEIPSLESLG----------------NIHISTVQRAAESLLEIDYAELEN 208
            ..|.|.        ..::|..:|||                ...:|.:|||..|.....:.|:..
  Rat   152 THSESE--------LLQVPLSDSLGPPLQSSAPSSIKQPSPESPVSGLQRARPSPFCWPFCEISQ 208

  Fly   209 ATDGWSPDNRLGQGGFGDVYRGKWKQLDVAIKVMNYRSPNIDQKMVELQQSY-NELKYLNSIRHD 272
            .|..:|.:.|:|:||||.|||...:....|:|.:...:   |.:...::||: .|::.|:..||.
  Rat   209 GTCNFSEELRIGEGGFGCVYRAVMRNTTYAVKRLKEEA---DLEWTVVKQSFLTEVEQLSRFRHP 270

  Fly   273 NILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPALTWQQRFSISLGTARGIYFLHTA 337
            ||:...||..:.|..||||..:..||||.:|  |........|:|.||..|.|||||.|.|||
  Rat   271 NIVDFAGYCAESGFYCLVYGFLPNGSLEDQL--HLQTQACSPLSWPQRLDILLGTARAIQFLH-- 331

  Fly   338 RGTP-LIHGDIKPANILLDQCLQPKIGDFGLVR------EGPKSLDAVVEVNKVFGTKIYLPPEF 395
            :.:| |||||||.:|:|||:.|.||:|||||.|      ..|.....|.....|.||..|||.|:
  Rat   332 QDSPSLIHGDIKSSNVLLDERLMPKLGDFGLARFSRFAGANPSQSSTVARTCTVRGTLAYLPEEY 396

  Fly   396 RNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQNRMELLEKHLAAPM 460
            ....:|:...|.:|||:|:||...|::.. |....:| |.|.|.::.:..:..:.|........|
  Rat   397 IKTGRLAVDTDTFSFGVVILETLAGQRAV-RTQGAKT-KYLKDLIEDEAEEVGVTLKSTQPTLWM 459

  Fly   461 GKELDMCMCAIEAGLHCTALD-------PQ------------------DRPSMNAVLKRFE 496
            |...|.....|.|.::...||       ||                  .||.|..|.||.|
  Rat   460 GVATDAWTAPIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCMHRRAKKRPPMTQVYKRLE 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_476971.1	Death_Pelle	32..128	CDD:260021	21/80 (26%)
		STKc_IRAK	219..498	CDD:270968	107/311 (34%)
Irak1	XP_006229660.1	Death_IRAK1	17..100	CDD:260061	20/70 (29%)
		Protein Kinases, catalytic domain	219..522	CDD:473864	107/311 (34%)