Protein Alignment pll and Irak4

DIOPT Version :10

• Sequence 1: NP_476971.1
• Gene: pll / 43283
• FlyBaseID: FBgn0010441
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001100261.2
• Gene: Irak4 / 300177
• RGDID: 1305303
• Length: 461
• Species: Rattus norvegicus
• Alignment Length: 440
• Identity: 139/440 - (31%)
• Similarity: 204/440 - (46%)
• Gaps: 76/440 - (17%)

  Fly    34 IRLLPLPVRAQLCAHLDALDVWQQLATAVKLYP---DQVEQISSQK-----QRGRSASNEFLNIW 90
            :|.|.:.:..:|...:|..:.|::||.|:| .|   |:..|...::     |.|:|.:.|.|..|
  Rat    11 VRSLNVGILRKLSDFIDPQEGWKKLAVAIK-KPSGDDRYNQFHIRRFEALLQTGKSPTCELLFDW 74

  Fly    91 GGQYNHTVQTLFALFKKLKLH-NAMRLIKDYVSEDLHKYIPRSVPTISELRAAPDSSAKVNNGPP 154
             |..|.||..|..|..:::|. .|..|:.|.|.:.:|...||...|:::...
  Rat    75 -GTTNCTVGDLVDLLIQIELFAPATLLLPDAVPQAVHSLPPREAATVAQAHR------------- 125

  Fly   155 FPSSSGVSNSNNNRTSTT--------ATEEIPSLESLGNIHISTVQRAAESLLEIDYAELENATD 211
             |.      ...|||:.|        .:.|:|...|.|:   .:|:.:........:.||::.|:
  Rat   126 -PC------QEKNRTTVTPALAQKLEPSCELPDSSSPGH---QSVEFSDTRFHSFSFYELKSITN 180

  Fly   212 GWSP------DNRLGQGGFGDVYRGKWKQLDVAIKVMNYRSPNIDQKMVEL------QQSYNELK 264
            .:..      .||:|:||||.||:|......||:|.:.        .|||:      ||...|:|
  Rat   181 DFDERPVSIGGNRMGEGGFGVVYKGCVNNTTVAVKKLG--------AMVEISTEELKQQFDQEIK 237

  Fly   265 YLNSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPALTWQQRFSISLGTAR 329
            .:...:|:|::.|.|:|......||||..|..|||..||   ...:..|.|:|..|..|:.|.|.
  Rat   238 VMAKCQHENLVELLGFSSDSDNLCLVYAYMPNGSLLDRL---SCLDGTPPLSWHMRCKIARGAAN 299

  Fly   330 GIYFLHTARGTPLIHGDIKPANILLDQCLQPKIGDFGLVREGPKSLDAVVEVNKVFGTKIYLPPE 394
            ||.|||....   ||.|||.|||||||....||.||||.|...| |...|..:::.||..|:.||
  Rat   300 GIRFLHENHH---IHRDIKSANILLDQDFTAKISDFGLARASAK-LAQTVMTSRIVGTTAYMAPE 360

  Fly   395 -FRNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQ 443
             .|.  :::...|:||||:||||:.||....|   ||...:.||| :|::
  Rat   361 ALRG--EITPKSDIYSFGVVLLELITGLAAVD---ENREPQLLLD-IKEE 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pll	NP_476971.1	Death_Pelle	32..128	CDD:260021	30/102 (29%)
		STKc_IRAK	219..498	CDD:270968	91/232 (39%)
Irak4	NP_001100261.2	Death_IRAK4	9..108	CDD:260060	29/98 (30%)
		STKc_IRAK4	172..458	CDD:271060	96/254 (38%)