Protein Alignment TTLL6B and TTLL4

DIOPT Version :10

• Sequence 1: NP_651549.1
• Gene: TTLL6B / 43282
• FlyBaseID: FBgn0039501
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: XP_016860876.1
• Gene: TTLL4 / 9654
• HGNCID: 28976
• Length: 1226
• Species: Homo sapiens
• Alignment Length: 481
• Identity: 155/481 - (32%)
• Similarity: 237/481 - (49%)
• Gaps: 72/481 - (14%)

  Fly   161 ISKTLG---YKLVKESKMWNILWSDSFPGVELFKNMKRFQQINHFPGMIEICRKDLLSRNLNRML 222
            :.:|:|   :|:.|.:..|...|........ |::::..|::|||||..:|.|||.|.|||:||.
Human   619 VKQTIGRSHFKISKRNDDWLGCWGHHMKSPS-FRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQ 682

  Fly   223 KIF-PQDYKIFPKTWMLPADYGDAMNYA--LNHKRTFILKPDSGAQGRGIWLTNDLKTIGPHERL 284
            ..| .:::..||::::||.| ...:..|  .:.::.:|:||.:.|:|.||.:.:....:.....|
Human   683 SRFGKKEFSFFPQSFILPQD-AKLLRKAWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPL 746

  Fly   285 ICQTYIHRPLLIDGYKFDLRVYTLITSVDPLRIFVYNEGLARFATNKYVEPTPGNANDLYMHLTN 349
            :.|.|:|:|.||.|.|||||:|..:||.|||||:::::||.|||:.|| .|:..:..:.:|||||
Human   747 LVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSDGLVRFASCKY-SPSMKSLGNKFMHLTN 810

  Fly   350 YSVNKRNSHYEL-CDNDDC-GSKRKLSAINNWMRRHNYDVEEFWSNVDDVIIKTVLSAWP----V 408
            |||||:|:.|:. .|...| |.|..|.|:.|::.:...:.:..|..:.||::||::|:.|    :
Human   811 YSVNKKNAEYQANADEMACQGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSL 875

  Fly   409 LKHNYHACFPGHDKIQACFEILGFDILVDWKLKPYILEVNHSPSFHTNEQVDREVKRPLIRDTLN 473
            ||......:       :|.|:.||||::|..|||::||||.|||.|::..:|..:|..:|||.||
Human   876 LKMYVRRPY-------SCHELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLN 933

  Fly   474 LVSTVLADKRQILKEDR--KRVKQRLLKIRGDPPVQRPRLGGGTSKPKIDAQKGS---------P 527
            |...||.:...|:....  ......|....||.....|.        .:.|||..         |
Human   934 LAGFVLPNAEDIISSPSSCSSSTTSLPTSPGDKCRMAPE--------HVTAQKMKKAYYLTQKIP 990

  Fly   528 DAQ----------PVDVE--PEAEDHGPLAQQIAWEESHLGNFRKIMPPPDLSKLDYYTRFYAQS 580
            |..          |.||.  .|.||          |.|..|.|.:|.|....|:   |.||:.|.
Human   991 DQDFYASVLDVLTPDDVRILVEMED----------EFSRRGQFERIFPSHISSR---YLRFFEQP 1042

  Fly   581 HQVSIFAETAASK------KREDLAR 600
            ...:|.......|      |..||.|
Human  1043 RYFNILTTQWEQKYHGNKLKGVDLLR 1068

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6B	NP_651549.1	TTL	196..486	CDD:397308	115/298 (39%)
TTLL4	XP_016860876.1	TTL	654..946	CDD:397308	115/300 (38%)