Protein Alignment TTLL6B and TTLL2

DIOPT Version :9

• Sequence 1: NP_651549.1
• Gene: TTLL6B / 43282
• FlyBaseID: FBgn0039501
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: NP_114155.4
• Gene: TTLL2 / 83887
• HGNCID: 21211
• Length: 592
• Species: Homo sapiens
• Alignment Length: 601
• Identity: 163/601 - (27%)
• Similarity: 251/601 - (41%)
• Gaps: 146/601 - (24%)

  Fly    94 PSSGENSPMPAEEAKLQGFIQLNNKTYRVECPTRVLNPPM--NVDEERPASETKSTICVSNSRYA 156
            |..|.  |.|..|.|.:..:...::      |:..|..|:  .|||..|               |
Human    56 PRRGR--PTPTLEKKKKPHLMAEDE------PSGALLKPLVFRVDETTP---------------A 97

  Fly   157 MIGKISKTLGY----KLVKESKMWNILWSDSFPGVELFKNMKRFQQINHFPGMIEICRKDLLSRN 217
            ::..:....|:    |..:.::.||:.|..|...:....::|.:||:||.||..::.|||.|:::
Human    98 VVQSVLLERGWNKFDKQEQNAEDWNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKH 162

  Fly   218 LNRMLKIFPQD-YKIFPKTWMLPADYGDAM------NYALNHKRTF-ILKPDSGAQGRGIWLTND 274
            |..|.:::... |:..|.|:::|.||...:      ...|..|.:: |.||...::||||.:.:|
Human   163 LKHMRRMYGTSLYQFIPLTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSD 227

  Fly   275 LKTIGPHERLICQTYIHRPLLIDGYKFDLRVYTLITSVDPLRIFVYNEGLARFATNKYVEPTPGN 339
            .|.....:..|.|.||..||||..||.|||:|..:|...||.|:||.|||.||||.|:   ...|
Human   228 FKDFIFDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKF---DLSN 289

  Fly   340 ANDLYMHLTNYSVNKRNSHYE-LCDNDDCGSKRKLSAINNWMRRHNYDVEE--FWSNVDDVIIKT 401
            ..:.|.||||.|:||..:.|| :.:....|.|..||...:::|  ::||::  .|..:..::|.|
Human   290 LQNNYAHLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLR--SWDVDDLLLWKKIHRMVILT 352

  Fly   402 VLSAWPVLKHNYHACFPGHDKIQACFEILGFDILVDWKLKPYILEVNHSPSFHTNEQVDREVKRP 466
            :|:..|.:.      |..:     |||:.|||||:|..|||::||||:||:...:...|..|||.
Human   353 ILAIAPSVP------FAAN-----CFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRK 406

  Fly   467 LIRDTLNLVSTVLADKRQILKEDRKRVKQRLLKIRGDPPVQRPRLGGGTSKPKIDAQKG------ 525
            |:.|.::|:         .|...|...::......|:              ..|||.|.
Human   407 LVHDIIDLI---------YLNGLRNEGREASNATHGN--------------SNIDAAKSDRGGLD 448

  Fly   526 SPDAQPVD---------------------VEPEAEDHGPLAQQIAWEESHLGNFRKIMP------ 563
            :||..|.|                     |.|||.....|..:::.::.||..  :.||
Human   449 APDCLPYDSLSFTSRMYNEDDSVVEKAVSVRPEAAPASQLEGEMSGQDFHLST--REMPQSKPKL 511

  Fly   564 ----PPDLSKLDYYTRFYAQSHQ--------------------------VSIFAETAASKKREDL 598
                .|..:.:.|.:.|  |||.                          |..|.|......|..|
Human   512 RSRHTPHKTLMPYASLF--QSHSCKTKTSPCVLSDRGKAPDPQAGNFVLVFPFNEATLGASRNGL 574

  Fly   599 ARKMRIQLEEKKAKQQ 614
            ..|..||..:|...:|
Human   575 NVKRIIQELQKLMNKQ 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6B	NP_651549.1	TTL	196..486	CDD:281171	106/300 (35%)
TTLL2	NP_114155.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	51..77		6/22 (27%)
		TTL	140..412	CDD:281171	105/287 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250453at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920