DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TTLL6B and Ttll1

DIOPT Version :9

Sequence 1:	NP_651549.1	Gene:	TTLL6B / 43282	FlyBaseID:	FBgn0039501	Length:	720	Species:	Drosophila melanogaster
Sequence 2:	XP_006242165.1	Gene:	Ttll1 / 362969	RGDID:	1309124	Length:	431	Species:	Rattus norvegicus

Alignment Length:	407	Identity:	121/407 - (29%)
Similarity:	190/407 - (46%)	Gaps:	81/407 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 GYKLVKESKMWNILWSDSFPGVELFKN---------MKRFQQINHFPGMIEICRKDLLSRNLNRM 221
            |:..|.|::.||..|.    .|:..:|         :...|.:||||...|:.||||:.:|:.|.
  Rat    32 GWVQVTENEDWNFYWM----SVQTIRNVFSVETGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRY 92

  Fly   222 LKIFPQD--------------YKIF-PKTWMLPADYG-DAMNYALNHKRTFILKPDSGAQGRGIW 270
            .|...::              |..| |.|:||||||. ....:..:...|:|:||...|||:||:
  Rat    93 RKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIF 157

  Fly   271 LTNDLKTI---------------GPHERLICQTYIHRPLLIDGYKFDLRVYTLITSVDPLRIFVY 320
            |.|.|..|               ...|..:...||:.||||.|.|||||:|.|:::..|||.::|
  Rat   158 LINKLSQIKKWSRDSKTSSFVSQSTKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMY 222

  Fly   321 NEGLARFATNKYVEPTPGNANDLYMHLTNYSVNKRNSHYELCDNDDCGSKRKLSAINNWMR--RH 383
            ..|..||.|.||. |:....:::::||||.::.|....|    |...|.|..::.:..::.  |.
  Rat   223 KLGFCRFCTVKYT-PSTSELDNMFVHLTNVAIQKHGEDY----NHIHGGKWTVNNLRLYLESTRG 282

  Fly   384 NYDVEEFWSNVDDVIIKTVLSAWPVLKHNYHACFPGHDKIQACFEILGFDILVDWKLKPYILEVN 448
            .....:.:..:..:|::::.:..||:.::.|           |||..|:||::|.||||:::|||
  Rat   283 REVTSKLFDEIHWIIVQSLKAVAPVMNNDKH-----------CFECYGYDIIIDDKLKPWLIEVN 336

  Fly   449 HSPSFHTNEQVDREVKRPLIRDTLNLV----------------STVLADKRQILKEDRKR--VKQ 495
            .|||..::...||.:|..||.||||:.                ..||.:...:..|:..:  ..:
  Rat   337 ASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGAE 401

  Fly   496 RLLKIRGDPPVQRPRLG 512
            |.|:.|...|| .||.|
  Rat   402 RELRSRPGQPV-GPRTG 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6B	NP_651549.1	TTL	196..486	CDD:281171	104/338 (31%)
Ttll1	XP_006242165.1	TTL	67..372	CDD:281171	102/320 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910