DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TTLL6B and TTLL3B

DIOPT Version :9

Sequence 1:	NP_651549.1	Gene:	TTLL6B / 43282	FlyBaseID:	FBgn0039501	Length:	720	Species:	Drosophila melanogaster
Sequence 2:	NP_609068.2	Gene:	TTLL3B / 33946	FlyBaseID:	FBgn0031853	Length:	756	Species:	Drosophila melanogaster

Alignment Length:	507	Identity:	111/507 - (21%)
Similarity:	178/507 - (35%)	Gaps:	181/507 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 VDEERPAS--ETKSTICVSNSRYAMIGKISKTL----GYKL----VKESKMWNILWSDSF--PGV 187
            |.|.:||.  ....||..:...:| :||:.|.:    .|.|    :|......|:.:.:|  ...
  Fly   294 VREHQPAELISENGTIFSTTLDFA-LGKVKKMVRHAEHYSLDDARIKPPTPAEIVENQTFMVQST 357

  Fly   188 ELFKNMKRFQQINHFPGMIEICRKDLLSRNLNRMLKIFPQDYKIFPKTWMLPADYGDAMNYALNH 252
            ::.|:..:|:.....  |.|..|  |....|:::..:.| ||:     |.             ..
  Fly   358 DVLKSNAKFKVSEKV--MAEYAR--LAGLYLDQIESLRP-DYR-----WD-------------GS 399

  Fly   253 KRTFILKPDSGAQGRGI-------------WLTNDLKTIGPHERLICQTYIHRPLLIDGYKFDLR 304
            :..:||||  |.|.|||             |.:|:     .:::.|.|.||.|||||...|||:|
  Fly   400 RNLWILKP--GYQSRGIGIVIRSSLDDILQWTSNN-----QNKKYIVQKYIERPLLIYRTKFDIR 457

  Fly   305 VYTLITSVD-PLRIFVYNEGLARFATNKYVEPTPGNANDL--YMHLTNYSVNKRNSHYELCDNDD 366
            .|.|:|..| .:.|:.|.:...||::.::      ..:||  .:||||.||.||   |:...|.|
  Fly   458 QYMLLTITDTKVSIWTYRDCYLRFSSQEF------TMDDLRESIHLTNNSVQKR---YKNKTNRD 513

  Fly   367 CGSKRKLSAINNWMRRHNYDVEEF-------------WSNVDDVIIKTVLSAWPVLKHNYHACFP 418
                .:|...|.|      .:::|             ||...:...:.:::.       ..|...
  Fly   514 ----SRLPKNNMW------SLDQFKNYLRIMGAPDGSWSKTYNGFKQNLVAV-------VMASLD 561

  Fly   419 GHDKIQACFEILGFDILVDWKLKPYILEVNHSPSFHTNEQVDREV----------------KRP- 466
            ..:.:|..||:.|.|.::|....|.::|:|.:|....:.::...:                |.|
  Fly   562 ETELLQNAFELYGCDFMLDEHYNPILIEINSTPDLSPSTEITARICPMVLKDCIRVVVDLPKNPT 626

  Fly   467 ------------------------------------------------LIRDTLNLVSTVLADK- 482
                                                            |:|..||.|.|....|
  Fly   627 AATGLFELAFEVNYSINKGADGKPLELNGKQMTLFENMPRMRNSPRTRLLRKILNNVKTSTTKKV 691

  Fly   483 RQILKEDRKRVKQRLLKIRGDPPVQRPRLGGGTSKPKIDAQKGS---PDAQP 531
            .::::...|.||....||              |.|.|:.|..||   ..|||
  Fly   692 EKVVEAPAKNVKNPTAKI--------------TKKKKLSASAGSSTAASAQP 729

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6B	NP_651549.1	TTL	196..486	CDD:281171	81/384 (21%)
TTLL3B	NP_609068.2	TTL	325..626	CDD:281171	79/356 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450548
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840