Protein Alignment TTLL6B and TTLL4B

DIOPT Version :10

• Sequence 1: NP_651549.1
• Gene: TTLL6B / 43282
• FlyBaseID: FBgn0039501
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Alignment Length: 702
• Identity: 170/702 - (24%)
• Similarity: 288/702 - (41%)
• Gaps: 159/702 - (22%)

  Fly    32 HVVRALDMALN------------EQPCL---DREWFSPEQSPPLQPMSP---------RRRMKKT 72
            ||...:.::||            :.||.   |..::....|......:|         .|:.|.|
  Fly   331 HVASYVGVSLNKGAGHDNDRKHEDDPCAAIDDINYYDDSDSEEEYVGTPFFLEEDNTETRQSKHT 395

  Fly    73 RCLKRRTAADKQV----DDNSPYYGPSSGENSPMPAEEAKLQGFIQLNNKTYRVECPTRVLNPPM 133
            |.|.::|.:.:.|    .:.|.|:.|   |....|:....:..::...:...:        .|||
  Fly   396 RLLPQKTPSKESVRTTDSEASVYFRP---EAILSPSLFPHVPPYLNFTSHADK--------GPPM 449

  Fly   134 NVDEERPASETKSTICVSNSRYAMIGKISKTLGYKLVKESKMWNILWSDSF--PGVELFKNMKRF 196
            .....|......|.:...     ::.::....|::::|.:..|..:|....  ||   |:.::..
  Fly   450 PAALHRVLKWKLSPVMPK-----IVKRVVLNSGFRIIKNTTDWMAVWEKHMKSPG---FRTIRSH 506

  Fly   197 QQINHFPGMIEICRKDLLSRNL-NRMLKIFPQDYKIFPKTWMLPADYGDAMN-YALNHKR--TFI 257
            |:.||.||...|.|||.:.|:: |.|.|...:::....|::::|.|...... :..|..:  .:|
  Fly   507 QKYNHIPGSFRIGRKDTMWRSIYNNMKKFGKKEFGFMQKSYIMPDDLESLRQVWPKNASKLTKWI 571

  Fly   258 LKPDSGAQGRGIWLTNDLKTIGPHERLICQTYIHRPLLIDGYKFDLRVYTLITSVDPLRIFVYNE 322
            :||.:.|:|.||.:.|..........|:.|.||.|||||:..|||:|:|.::||::||||::|.:
  Fly   572 VKPPASARGTGIRIVNKWSQFPKDRPLVVQKYIERPLLINDNKFDMRLYVVLTSINPLRIYMYKD 636

  Fly   323 GLARFATNKYVEPTPGNANDLYMHLTNYSVNKRNSHYELCDNDD---C-GSKRKLSAINNWMRRH 383
            ||||||:.||.... .|.::..|||||||:||.:.:|  ..|:|   | |.|..|.::.:.:...
  Fly   637 GLARFASVKYSSEL-SNLDERCMHLTNYSINKFSQNY--AKNEDFNACQGHKWTLQSLWSCLENR 698

  Fly   384 NYDVEEFWSNVDDVIIKTVLSAWPVLKHNYHACFPGHDKIQ---ACFEILGFDILVDWKLKPYIL 445
            ..:.:..|:.:.:::||.::|....|...|      ...:.   .|||:.|||:|:|..|.|::|
  Fly   699 GVNTKRLWATLRNLVIKGIVSGESGLNRMY------RQNVNFRYNCFELFGFDVLLDENLVPWLL 757

  Fly   446 EVNHSPSFHTNEQVDREVKRPLIRDTLNLVSTVLADKRQILKEDRKRVKQRLLKIRGDPPVQRPR 510
            |:|.|||.|:...:|..||.|||:..||   |.|                          .|.|
  Fly   758 EINISPSLHSELPLDLHVKGPLIQAVLN---TAL--------------------------YQVP- 792

  Fly   511 LGGGTSKPKIDAQKGSPDAQPVDVEPEAEDHGPLA-----------------------QQIAWEE 552
                   ||::      :.|..|:..|....|||.                       :.|.:.|
  Fly   793 -------PKLN------ERQQADILEELNLTGPLCHDKRIFTTCLTAEEVRKHNQYTNRSIEFRE 844

  Fly   553 SHLGNFRKIMPPPD----------LSKLDYYTRFY--AQSHQVSIFAETAASKKREDLARKMRIQ 605
            .::......:.|.|          |::.....|.:  |.:|....:.|.|....|      :...
  Fly   845 EYVDTILDNLLPDDVRCLIVAEDELARCQPLERIFPTAGTHVYLRYVENARYYNR------LLDA 903

  Fly   606 LEEKKAKQQQMLNGKAKRDARKRHTVLLPRAVREK------NRINFFRLREN 651
            .|.|.||.::|......|..|.::.:.:..|..||      ..|:...:|::
  Fly   904 WETKYAKNREMGIALLSRYCRDKYHLQVSDAAMEKEPNVALTEIDMLHVRKD 955

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6B	NP_651549.1	TTL	196..486	CDD:397308	104/300 (35%)
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	108/345 (31%)