DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TTLL6B and Ttll7

DIOPT Version :9

Sequence 1:	NP_651549.1	Gene:	TTLL6B / 43282	FlyBaseID:	FBgn0039501	Length:	720	Species:	Drosophila melanogaster
Sequence 2:	XP_038959801.1	Gene:	Ttll7 / 310982	RGDID:	1566117	Length:	886	Species:	Rattus norvegicus

Alignment Length:	550	Identity:	193/550 - (35%)
Similarity:	311/550 - (56%)	Gaps:	54/550 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 MPA--EEAKLQGF--IQLNNKTYRVECPTRVLNPPMNVDEERPASETKS----TICVSNSRYAMI 158
            ||:  ::..:||.  ::||.:.            |.:...:|...:.|.    |..|:.:::.::
  Rat     1 MPSLPQDGVIQGSSPLELNTEL------------PYHCTMKRKVRKKKKKGIITANVAGTKFEIV 53

  Fly   159 GKISKTLGY-KLVKESKMWNILWSDSFPGVELFKNMKRFQQINHFPGMIEICRKDLLSRNLNRML 222
            ..:...:|: |...|.:..|::|.|:....|...:::.:|:|||||||.||||||.|:||:.:|:
  Rat    54 RLVIDEMGFIKTPDEDETSNLIWCDAAVQQEKITDLQNYQRINHFPGMGEICRKDFLARNMTKMI 118

  Fly   223 KIFPQDYKIFPKTWMLPADYGDAMNYA--LNHKR---TFILKPDSGAQGRGIWLTNDLKTIGPHE 282
            |..|.||...|:||:.|::|....||.  |..||   |||:||.:||.|.||.|..:...|...:
  Rat   119 KSRPMDYTFVPRTWIFPSEYTQFQNYVKELKKKRKQKTFIIKPANGAMGHGISLIRNGDKIPSQD 183

  Fly   283 RLICQTYIHRPLLIDGYKFDLRVYTLITSVDPLRIFVYNEGLARFATNKYVEPTPGNANDLYMHL 347
            .||.|.||.:|.|::|||||||:|.|:||.|||:||:|::||.|..|.||:.|...|...|||||
  Rat   184 HLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHL 248

  Fly   348 TNYSVNKRNSHYELCDNDDCGSKRKLSAINNWMRRHNYDVEEFWSNVDDVIIKTVLSAWPVLKHN 412
            |||||||.|..:|..:.:|.||||.:.....:::.:.:||.:|||::.::::||::.|.|.:.|.
  Rat   249 TNYSVNKHNERFERNETEDKGSKRSIKWFTEFLQANQHDVTKFWSDISELVVKTLIVAEPHVLHA 313

  Fly   413 YHACFPGH--DKIQACFEILGFDILVDWKLKPYILEVNHSPSFHTNEQVDREVKRPLIRDTLNLV 475
            |..|.||.  .....|||:||||||:|.||||::||:|.:|||.|::::|.:|||.::.:.|.|:
  Rat   314 YRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLL 378

  Fly   476 STVLADKRQILKEDRKRVKQRLLKIRGDPPVQRPRLGGGTS-----KPKIDAQKGSPDAQPVDVE 535
            :...:|||:.|.:.:...::||.   |..|::  ||..|:|     :.:::.:|.....:.:.|.
  Rat   379 NIRTSDKRKNLAKQKAEAQRRLY---GQNPIR--RLSPGSSDWEQQRHQLERRKEELKERLLQVR 438

  Fly   536 PE--AEDHGPLAQQIAWEESHLGNFRKIMPPPDLSKLDYYTRFYAQSHQVSIFAE-TAASKKRED 597
            .:  .|:|         |..|:||:|:|.||.|.:.|:.|....|.:.|..:... |:..::..:
  Rat   439 KQISQEEH---------ENRHMGNYRRIYPPEDKTLLEKYEGLLAVAFQTFLSGRATSFHREMNN 494

  Fly   598 LARKMR----IQLEEKKAKQQQMLNGKAKR 623
            ..:|||    :.|.|:.....:.|.||..|
  Rat   495 PLKKMREEDLLDLLEQCEIDDEKLMGKTTR 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6B	NP_651549.1	TTL	196..486	CDD:281171	139/296 (47%)
Ttll7	XP_038959801.1	TTL	91..376	CDD:397308	134/284 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1251554at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920