Protein Alignment TTLL6B and Ttll13

DIOPT Version :9

• Sequence 1: NP_651549.1
• Gene: TTLL6B / 43282
• FlyBaseID: FBgn0039501
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: XP_006540976.1
• Gene: Ttll13 / 269954
• MGIID: 1920845
• Length: 849
• Species: Mus musculus
• Alignment Length: 676
• Identity: 272/676 - (40%)
• Similarity: 377/676 - (55%)
• Gaps: 107/676 - (15%)

  Fly    94 PSSGENSPMPAEEAKLQGFIQLNNKTYRVECPTRVLNPPMNVDEE-----RPASETKSTICVSNS 153
            |:|.:.:...|:..:.:..:.|:....::  |.::|:.....|.|     |........|.::|.
Mouse    33 PNSTQQALRKADYKEFENGVALSVVAKKI--PKKILSATDTDDLEVGRRRRKRKRRPLAINLTNC 95

  Fly   154 RY---------------------AMIGKISKTLGYKLVKESKMWNILWSDSFPGVELFKNMKRFQ 197
            :|                     :.:.:.::..|.|.|.|.:.|.:.|:|....:|...:|||||
Mouse    96 KYESARVPGFMAGTQAGSVDLPVSTVRRAAQMCGLKEVGEDEEWTVYWTDCSVSLERVMDMKRFQ 160

  Fly   198 QINHFPGMIEICRKDLLSRNLNRMLKIFPQDYKIFPKTWMLPADYGDAMNYALNHK-RTFILKPD 261
            :|||||||.||||||||:||||||.|::|.:|.|||:||.|||||||...|....| ||:|.|||
Mouse   161 KINHFPGMTEICRKDLLARNLNRMQKLYPTEYNIFPRTWCLPADYGDFQAYGRQRKTRTYICKPD 225

  Fly   262 SGAQGRGIWLTNDLKTIGPHERLICQTYIHRPLLIDGYKFDLRVYTLITSVDPLRIFVYNEGLAR 326
            ||.|||||::|...|.|.|.|.:|||.||.:|.||||:|||:|:|.||||.||||||:|.|||||
Mouse   226 SGCQGRGIFITRTPKEIKPGEHMICQQYITKPFLIDGFKFDMRIYVLITSCDPLRIFMYEEGLAR 290

  Fly   327 FATNKYVEPTPGNANDLYMHLTNYSVNKRNSHYELCDNDDCGSKRKLSAINNWMRRHNYDVEEFW 391
            |||..||||:..|..::.||||||::||.|.::  ..:|..|||||||.:|.|:|.|::|.:|.|
Mouse   291 FATMPYVEPSHNNLEEVCMHLTNYAINKHNENF--VRDDAVGSKRKLSTLNAWLREHSHDPQELW 353

  Fly   392 SNVDDVIIKTVLSAWPVLKHNYHACFPGH--DKIQACFEILGFDILVDWKLKPYILEVNHSPSFH 454
            .:::|:||||::||..||:|||..|||.:  ....|||||||||||:|.||||::|||||||||.
Mouse   354 GDIEDIIIKTIISAHSVLRHNYRTCFPQYLCGGTCACFEILGFDILLDHKLKPWLLEVNHSPSFT 418

  Fly   455 TNEQVDREVKRPLIRDTLNLVSTVLADKRQILKEDRKRVKQRLLKIRGDPPVQRPRLGGGTSKPK 519
            |:.::|||||..|:.|.:|||:....||:::::||::|||:||.     |..|:||   .|.:.:
Mouse   419 TDSRLDREVKDALLCDAMNLVNLRGCDKKKVIEEDKRRVKERLF-----PCHQQPR---ETRREQ 475

  Fly   520 IDAQKGSPDAQPVDVEPEAEDHGPLAQQIAWEESHLGNFRKIMPPPDLSKLDYYTRFYAQSHQVS 584
            .:..:.:                 :..|..:|:||||.:|:|.|.||..|   |..|:  .|..|
Mouse   476 FELSQAA-----------------MHDQERYEDSHLGGYRRIYPGPDSEK---YAPFF--KHNGS 518

  Fly   585 IFAETAASKKREDLARKMRIQLEEKKAKQQQMLN-GKAKRDARKRH---------------TVLL 633
            :|.||||||.||:.||:   ||||.:.||:|..| |..||...|..               |.:|
Mouse   519 LFQETAASKAREECARQ---QLEEIRLKQEQQENPGTKKRKENKEQNQGESAGEKSRSRTATRVL 580

  Fly   634 PRAVREKNRINFFRLRE----------NWSPGFISDAEERLRHTWLHMRAEAIRTLKITENIYSN 688
            ..::..:||   .|.:|          ...|..|.:.||..|...|..|...||:|.|.|.:...
Mouse   581 ATSLAYRNR---NREKEVSGLLPVQLDTTQPQDIVEEEELERMKLLLQRENLIRSLGIVEQLTRM 642

  Fly   689 LYETGLLTNTDMVVYPHLYHNLQHGY 714
            ||.:            |..|...|.|
Mouse   643 LYPS------------HRSHRKLHEY 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6B	NP_651549.1	TTL	196..486	CDD:281171	174/292 (60%)
Ttll13	XP_006540976.1	TTL	154..439	CDD:281171	173/286 (60%)
		DNA_S_dndD	<466..635	CDD:274475	59/199 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	368	1.000	Domainoid score	I915
eggNOG	1	0.900	-	-		E1_KOG2158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	458	1.000	Inparanoid score	I1562
Isobase	1	0.950	-	0	Normalized mean entropy	S4788
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1251554at2759
OrthoFinder	1	1.000	-	-		FOG0005255
OrthoInspector	1	1.000	-	-		mtm8900
orthoMCL	1	0.900	-	-		OOG6_102355
Panther	1	1.100	-	-	LDO	PTHR12241
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3776
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.780