DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5984 and alpha-Spec

DIOPT Version :9

Sequence 1:	NP_651548.1	Gene:	CG5984 / 43281	FlyBaseID:	FBgn0039500	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001261286.1	Gene:	alpha-Spec / 38231	FlyBaseID:	FBgn0250789	Length:	2457	Species:	Drosophila melanogaster

Alignment Length:	153	Identity:	35/153 - (22%)
Similarity:	55/153 - (35%)	Gaps:	60/153 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 AASSASACSSSGSGLEGNSPE---EGGIFGRYQRTPDADAYPSE--SPRVYVAPELTDAGKVQLL 73
            |||::|..|.||.  |.:..|   ..|.||.:::      :.:|  ....|.:||:.:  |::.|
  Fly  1349 AASTSSIASPSGD--EEHRTEIDARAGTFGAFEQ------FGNELLQANHYASPEIKE--KIEDL 1403

  Fly    74 HFPSGAVRVNSPLGFIIKRNGVKGNFEVRVEGPSGQPIQPVRQQQLDPERFQIDCQL-------- 130
                  .:....|        .|...|.|::          .:|.||.:.:..||:|
  Fly  1404 ------AKAREDL--------EKAWTERRLQ----------LEQNLDLQLYMRDCELAESWMSAR 1444

  Fly   131 --------DAGAG-----LYKVH 140
                    ||.||     |.|.|
  Fly  1445 EAFLNADDDANAGGNVEALIKKH 1467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5984	NP_651548.1	Filamin	65..154	CDD:279024	19/97 (20%)
		Filamin	179..266	CDD:279024
		IG_FLMN	181..271	CDD:214720
alpha-Spec	NP_001261286.1	SH3_Alpha_Spectrin	974..1026	CDD:212742
		SPEC	1074..1287	CDD:238103
		SPEC	1182..1425	CDD:238103	23/109 (21%)
		SPEC	1426..1638	CDD:238103	11/42 (26%)
		SPEC	1533..1744	CDD:238103
		SPEC	1646..1850	CDD:238103
		SPEC	1852..2062	CDD:238103
		SPEC	1958..2176	CDD:238103
		SPEC	2072..2296	CDD:238103
		EFh	2311..2379	CDD:238008
		EFhand_Ca_insen	2386..2456	CDD:400872
		SPEC	48..258	CDD:238103
		SPEC	154..364	CDD:238103
		SPEC	261..470	CDD:238103
		SPEC	471..680	CDD:238103
		SPEC	682..893	CDD:238103
		Spectrin	893..>961	CDD:395348
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439916
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930