DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5984 and Dyb

DIOPT Version :9

Sequence 1:	NP_651548.1	Gene:	CG5984 / 43281	FlyBaseID:	FBgn0039500	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001097287.1	Gene:	Dyb / 36362	FlyBaseID:	FBgn0033739	Length:	816	Species:	Drosophila melanogaster

Alignment Length:	241	Identity:	52/241 - (21%)
Similarity:	80/241 - (33%)	Gaps:	70/241 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 FKVSQEMRLNTQAASSASACSSSGSGLEGNSPEEGGIFGRYQRTPDA----DAYPS------ESP 56
            |..||..:||..::...||.:::||.    :|..       .||..|    .|.||      ::|
  Fly   585 FSQSQLEQLNQISSDMRSAFAANGSA----TPPP-------MRTTTATANVSAIPSLNPISNQNP 638

  Fly    57 RVYVAPELTDAGKVQLLHFPSGAVRVNSPLGFIIKRNGVKGNFEVRVEGPSGQPIQPVRQQQ-LD 120
            .:....||.:|..    |..|....:.|.|      |..:|    |.:....||...:.|.: :.
  Fly   639 NLNPDAELNEAAD----HLTSAISHMVSDL------NAGRG----RAQQLGPQPASSIPQARFIM 689

  Fly   121 PERF------------QIDCQLDAGAGLYK------VHIKCNSVTLP-RSPFIIVAIAGATESID 166
            |..|            |.:|. |...|.|:      ..::|.....| .:.:.:...:|..|.
  Fly   690 PLEFRHIEGGESEDSSQCECN-DCECGEYEEVFRTDEDLECEGAAAPFGNAYSLFPTSGVHEE-- 751

  Fly   167 GKPASSSVPISDSDASRVQSRGLGLTHVSLVERN--EFTVDCGQAG 210
                      ...|.:..|...|...:..|..||  |..:|..|||
  Fly   752 ----------DHFDYTFGQGEELSQVNRILGYRNHPELFIDDEQAG 787

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5984	NP_651548.1	Filamin	65..154	CDD:279024	20/108 (19%)
		Filamin	179..266	CDD:279024	11/34 (32%)
		IG_FLMN	181..271	CDD:214720	10/32 (31%)
Dyb	NP_001097287.1	EF-hand_2	7..131	CDD:286194
		EF-hand_3	135..223	CDD:286195
		ZZ_dystrophin	232..280	CDD:239074
		Ribosomal_L29	436..482	CDD:279204
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439894
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930