DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5984 and Actn

DIOPT Version :9

Sequence 1:	NP_651548.1	Gene:	CG5984 / 43281	FlyBaseID:	FBgn0039500	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001259165.1	Gene:	Actn / 31166	FlyBaseID:	FBgn0000667	Length:	917	Species:	Drosophila melanogaster

Alignment Length:	214	Identity:	41/214 - (19%)
Similarity:	72/214 - (33%)	Gaps:	79/214 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 RNGVKGNFEVRVEGPSGQPI-QPVRQQQLDPERFQIDCQLD--AGAGLYKVHIKCNSVTLPRSPF 153
            |||:|  ..:.:|..||:.: :|.|.:....:...::..||  |..|::.|.|
  Fly    63 RNGLK--LMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSI------------ 113

  Fly   154 IIVAIAGATESIDG--------------KPASSSVPISDSDAS-----------------RVQSR 187
                  ||.|.:||              :.|...:.:.:..|.                 .||:.
  Fly   114 ------GAEEIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNF 172

  Fly   188 GL----GLTHVSLVERNEFTVDCGQAGSNMLLVGVLGQRGPCE------EVVVRHLGRGIHRVTY 242
            .|    ||...:|:.|:.         .:::....|.:..|.|      :|..::|.      ..
  Fly   173 HLSFKDGLAFCALIHRHR---------PDLIDYAKLSKDNPLENLNTAFDVAEKYLD------IP 222

  Fly   243 RVCDPGDYILVVKWGEQHV 261
            |:.||.|.|...|..|:.:
  Fly   223 RMLDPDDLINTPKPDERAI 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5984	NP_651548.1	Filamin	65..154	CDD:279024	15/64 (23%)
		Filamin	179..266	CDD:279024	20/110 (18%)
		IG_FLMN	181..271	CDD:214720	20/108 (19%)
Actn	NP_001259165.1	CH_ACTN_rpt1	31..135	CDD:409063	20/91 (22%)
		CH_ACTN_rpt2	139..252	CDD:409065	20/118 (17%)
		SPEC	302..525	CDD:238103
		SPEC	420..647	CDD:238103
		SPEC	538..760	CDD:238103
		EFh	775..842	CDD:238008
		EFhand_Ca_insen	847..913	CDD:400872
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439907
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930