Protein Alignment CG5984 and fln-1

DIOPT Version :10

• Sequence 1: NP_651548.1
• Gene: CG5984 / 43281
• FlyBaseID: FBgn0039500
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_001294364.1
• Gene: fln-1 / 176855
• WormBaseID: WBGene00022048
• Length: 2259
• Species: Caenorhabditis elegans
• Alignment Length: 382
• Identity: 91/382 - (23%)
• Similarity: 143/382 - (37%)
• Gaps: 131/382 - (34%)

  Fly    13 QAASSASACSSSG---SGLEGNSPEEGGIFGRYQ-RTPDA--------DAYPSESP-RVYVAPEL 64
            :|...|.|.:..|   :.||.....:|.....|: .||..        |.:..:|| :||:||..
 Worm  1881 EAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPAT 1945

  Fly    65 TDAGKVQLLHFPSGAVRVNSPLGFIIKRNGVKGNFEVRVEGPSGQ-------PIQ---------- 112
            .:..|::|..|....:.......|.:..:..||:.|.:|..|:.:       ||:
 Worm  1946 GEVRKLELAQFHGQGIPAGKAFTFTVLTHRAKGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFV 2010

  Fly   113 ----------------PVRQQQLDPERFQI-------------------------DCQL-----D 131
                            |:|:   .|.|.::                         .|:.     :
 Worm  2011 PKETGNHFIHVTLDGAPMRE---SPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTAN 2072

  Fly   132 AGAGL---------------------YKVH------------IKCNSVTLPRSPFII-------- 155
            ||||:                     |||.            :|.|.:..|.|||.|
 Worm  2073 AGAGILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELG 2137

  Fly   156 ---------VAIAGATESIDGKPASSSVPISDSDASRVQSRGLGLTHVSLVERNEFTVDCGQAGS 211
                     |.|....::..|..|  .||....||::|.::|.||..........|.:|.|.||:
 Worm  2138 GNGYNETSHVKIDAVAKTSKGTVA--VVPEYQGDAAKVTAKGAGLNKFFPGRPAAFQIDTGLAGT 2200

  Fly   212 NMLLVGVLGQRGPCEEVVVRHLGRGIHRVTYRVCDPGDYILVVKWGEQHVPGSPFSL 268
            |:|:|||:..:||||||||||.|.|.:..:||:.|.....:.:|:|::.:|||||::
 Worm  2201 NLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGFVFIKYGDKEIPGSPFAI 2257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5984	NP_651548.1	Filamin	65..154	CDD:395505	28/184 (15%)
		IG_FLMN	181..271	CDD:214720	37/88 (42%)
fln-1	NP_001294364.1	CH_dFLNA-like_rpt1	13..136	CDD:409160
		CH_FLN_rpt2	151..255	CDD:409079
		IG_FLMN	261..358	CDD:214720
		IG_FLMN	367..446	CDD:214720
		IG_FLMN	549..637	CDD:214720
		IG_FLMN	643..737	CDD:214720
		IG_FLMN	740..830	CDD:214720
		IG_FLMN	930..1020	CDD:214720
		IG_FLMN	<1406..1476	CDD:214720
		IG_FLMN	1484..1567	CDD:214720
		Filamin	1561..1650	CDD:395505
		IG_FLMN	1661..1750	CDD:214720
		Filamin	<1789..1842	CDD:395505
		IG_FLMN	1854..1944	CDD:214720	16/62 (26%)
		IG_FLMN	1959..2039	CDD:214720	12/82 (15%)
		IG_FLMN	2045..2133	CDD:214720	15/87 (17%)
		IG_FLMN	2170..2258	CDD:214720	37/88 (42%)