Protein Alignment CG17991 and MARCHF5

DIOPT Version :9

• Sequence 1: NP_651547.1
• Gene: CG17991 / 43279
• FlyBaseID: FBgn0039498
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_060294.1
• Gene: MARCHF5 / 54708
• HGNCID: 26025
• Length: 278
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 110/273 - (40%)
• Similarity: 170/273 - (62%)
• Gaps: 6/273 - (2%)

  Fly    19 LERCCWICFETDKEAGRQAWVNPCLCRGTNKWVHQSCISLWIDEKTRINNNLQAVSCPQCQTEYT 83
            |:|.||:||.||::.....||.||.|||:.|||||:|:..|:|||.| .|:...|:||||..||.
Human    10 LDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQR-GNSTARVACPQCNAEYL 73

  Fly    84 IAYPNLWIFDRALELTNDLILTNLYNCLANVFTVVFAYWSAVSFGAKTYLQITG-QEGHVHQIIQ 147
            |.:|.|......|:|.:.||........|.:. |...||:||::||.|.:|:.| :||  ..:::
Human    74 IVFPKLGPVVYVLDLADRLISKACPFAAAGIM-VGSIYWTAVTYGAVTVMQVVGHKEG--LDVME 135

  Fly   148 SGDLLVVLVGFPLISVVLILGRLIPWEDALLRFIRICYSLLRSLSMMCLGRKYDHQTEPYPSAPM 212
            ..|.|.:|:|.|.|.|:||||::|.|||.:||..|...:.|:.|:.:..|........|..:.|:
Human   136 RADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPL 200

  Fly   213 TEY-SASRVVCGAILLPTISMYVGRVLYSSVDDRLQQTLLGGLTFIAIKGFLKMYLMHSQYICRM 276
            .:: ||:|::|||::.|||:..||::::|||:..||:|:|||:.|:||||..|:|....||:.:.
Human   201 ADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQA 265

  Fly   277 KRRVLDYTKENLA 289
            .|::|:|.::..|
Human   266 HRKILNYPEQEEA 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17991	NP_651547.1	RINGv	22..79	CDD:128983	29/56 (52%)
MARCHF5	NP_060294.1	RING_CH-C4HC3_MARCH5	12..72	CDD:319615	31/60 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153119
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3053
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6573
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D426217at33208
OrthoFinder	1	1.000	-	-		FOG0003968
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X270
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.760