Protein Alignment CG17991 and Marchf11

DIOPT Version :10

• Sequence 1: NP_651547.1
• Gene: CG17991 / 43279
• FlyBaseID: FBgn0039498
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_001095298.1
• Gene: Marchf11 / 499558
• RGDID: 1559945
• Length: 398
• Species: Rattus norvegicus
• Alignment Length: 287
• Identity: 53/287 - (18%)
• Similarity: 99/287 - (34%)
• Gaps: 117/287 - (40%)

  Fly     4 NVAAPQASAGGDSTEL---------ERCCWICFETDKEAGRQAWVNPCLCRGTNKWVHQSCISLW 59
            :|.:.::|:.|.|.:.         :..|.|||: ..|.|.  .:|||.|.|:.::.||.|:..|
  Rat   138 SVCSSRSSSSGGSGDQRSGHQHQHHQPICKICFQ-GAEQGE--LLNPCRCDGSVRYTHQLCLLKW 199

  Fly    60 IDEKTRINNNLQAVSCPQCQTEYTIAYPNLWIFDRALELTNDLILTNLYNCLANVFTVVFAYWSA 124
            |.|:       .:.:|..|...|.:.         |:::...                  ..|.:
  Rat   200 ISER-------GSWTCELCCYRYHVT---------AIKMKQP------------------CQWQS 230

  Fly   125 VSFGAKTYLQITGQEGHVHQIIQSGDLLVVLVG--FPLISVVLILGRLIP----WEDALLRFIRI 183
            :|        ||        :::...::.|::|  |.:.||..:|.....    |:...:.| :|
  Rat   231 IS--------IT--------LVEKVQMIAVILGSLFLIASVTWLLWSAFSPYAVWQRKDILF-QI 278

  Fly   184 CYSLLRSLSMMCLG-------------------------RKYDHQTEPYPSA------------P 211
            ||.:...:.::|:|                         ..||..|:...|:            |
  Rat   279 CYGMYGFMDLVCIGLIVHEGAAVYRVFKRWRAVNLHWDVLNYDKATDIEESSRGESSTSRTLWLP 343

  Fly   212 M-----------TEYSASRVVCGAILL 227
            :           |:.::.|..||.:||
  Rat   344 LSALRNRNLVHPTQLTSPRFQCGYVLL 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17991	NP_651547.1	RING_CH-C4HC3_MARCH5	21..82	CDD:438361	19/60 (32%)
Marchf11	NP_001095298.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..158		4/19 (21%)
		RING_CH-C4HC3_MARCH11	164..223	CDD:438460	21/77 (27%)
		YXXL motif	367..370		0/2 (0%)
		PDZ-binding	395..398