Protein Alignment CG31064 and PIB2

DIOPT Version :9

• Sequence 1: NP_001287560.1
• Gene: CG31064 / 43277
• FlyBaseID: FBgn0051064
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: NP_011492.3
• Gene: PIB2 / 852861
• SGDID: S000002991
• Length: 635
• Species: Saccharomyces cerevisiae
• Alignment Length: 557
• Identity: 109/557 - (19%)
• Similarity: 206/557 - (36%)
• Gaps: 144/557 - (25%)

  Fly   426 LVGLNVIDCNLCVKEEDLDSQQ----GVIDFSLYLRSSSRNADAAPEDS---------------- 470
            :..|:.:.....:|||:.|..:    ||   .|..|:.........|:|
Yeast     1 MTALHSVSKTPAIKEEEEDGDERDGRGV---PLGPRNHDYRGRKGDEESGADTVTSPITFEKKKI 62

  Fly   471 APPALLDATGQGNMIAVLDQKNYIEELNRHLNATVGNLQAKVESLTTTNA---LMKEDLAIARNS 532
            ||.|  ....:.::::.:..|:.:   |:|       .|.:::..::|.|   .:.....|...:
Yeast    63 APRA--STHSEQSILSSISLKSMV---NQH-------RQQQLQQESSTGAGTGFVDRKQQIQSPA 115

  Fly   533 LLALQAENQAMRQSTSAGDNNSTGSGGSSDKDKEKASEEL------VEERRKNSELEKELKLQVS 591
            ::::..:|.| .::..:..::..|. |..|..|..||:|:      .:::|.|.||:....: |.
Yeast   116 MVSILRKNSA-EENVRSSHSSKLGE-GQIDGRKASASKEIGKTLPFTDDQRSNPELDPTNSV-VD 177

  Fly   592 LKAESDMAMKLLEKDIHEKQDTIVSLRRQLDDIKQINL--EMYRKLQDCKASLTHKTELMTKLEV 654
            :....:...|.:..::.:..|       ..|:::|.||  :..|||...|.:.:....| :|...
Yeast   178 VSRGKNTKSKTVFNELEDDAD-------DDDEVRQKNLTTQALRKLSSFKMNASSNLRL-SKENK 234

  Fly   655 QKEDMASTIDQLEKKWSHDKSNLGEILKTTSQTLTTQ--------VTASEERAARAEAESRIERE 711
            .||..:|:...:....:....|:.:.|.||:.:..:|        :..|...||:...:..:.:.
Yeast   235 AKESSSSSTSSVSSSSTSKVENIVDKLTTTNSSSMSQLRFGNTNVIIDSVNHAAKPPHQQMLRKP 299

  Fly   712 WRISLQ---------------EKELKLKEKIAN------LQGCLKELSEEKERNGKLKADLDKVR 755
               ||:               .|......:|:|      :...|:::||....|..|   |:...
Yeast   300 ---SLEFLPQPASSTNLNFNSNKHKSNVRQISNPKKPLYIPAVLRKVSETNITNDDL---LNATL 358

  Fly   756 TQWSEAQTTLEELGIQLSVSKLKVSEMQDQER-----RQRQLLSGSAQSLQAMPEAVGS------ 809
            :.:.:..:.||.   ..:.||.:.:.:|:...     .|..:.|.::..|::....:.|
Yeast   359 SSYYKKASNLEH---GFNPSKSQSASVQNANNLRIISSQSSVQSNTSSILESYKNKISSYLFPNS 420

  Fly   810 ----------PGI---------------WAPDSIATHCTACEREFNLTRRKHHCRSCGEIFCKAC 849
                      |.|               |.|||....|..|.:.|.|..||||||.||:|||:..
Yeast   421 IPNSDRINLIPTISNRNSARVNPPTKDHWIPDSKRNSCRYCHKPFTLWERKHHCRHCGDIFCQDH 485

  Fly   850 SEHTLPL-----------LNAQG--QPGKPVRVCDNC 873
            ..|.|.|           ||..|  ..|...::||:|
Yeast   486 LRHWLYLDSQANFIMINELNNGGINGGGTLCKICDDC 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN	316..439	CDD:280855	1/12 (8%)
		CASP_C	495..>634	CDD:285395	26/149 (17%)
		FYVE_RUFY1_like	813..874	CDD:277261	29/74 (39%)
PIB2	NP_011492.3	FYVE	446..530	CDD:214499	29/77 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2108
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030