Protein Alignment CG31064 and PLEKHF1

DIOPT Version :10

• Sequence 1: NP_001287560.1
• Gene: CG31064 / 43277
• FlyBaseID: FBgn0051064
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: XP_005259313.1
• Gene: PLEKHF1 / 79156
• HGNCID: 20764
• Length: 364
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 53/220 - (24%)
• Similarity: 85/220 - (38%)
• Gaps: 60/220 - (27%)

  Fly   678 GEILKTTSQTLTTQVTASEERAARAEAESRI----------------EREWR----ISLQEKELK 722
            |:.|....:.|..:...::|  .|.:|:.||                :|::|    |.|:|..|:
Human   111 GQPLALPGRVLLGEGVLTKE--CRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLE 173

  Fly   723 LKEKIANLQGCLKELSEEKERNGKLKADLDKVRTQWSEAQTTLEELGIQLSVSKLKVSEMQDQER 787
            |..:  .||...:.:.:..:::..:.|.....|.:|                    :|.:::..|
Human   174 LLPE--TLQAKNRWMIKTAKKSFVVSAASATERQEW--------------------ISHIEECVR 216

  Fly   788 RQRQLLSGSAQSLQAMPEAVGSPGIWAPDSIATHCTAC-EREFNLTRRKHHCRSCGEIFCKACSE 851
            ||.:.......:..|.|        |.||.....|..| :..|:...|:||||.||.:.|..||.
Human   217 RQLRATGRPPSTEHAAP--------WIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSR 273

  Fly   852 H--TLPLLNAQGQPGKPVRVCDNCY 874
            .  .||.|:.     ||||||..||
Human   274 QRFLLPRLSP-----KPVRVCSLCY 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN_RUFY1_like	281..436	CDD:439043
		Smc	<562..>807	CDD:440809	26/148 (18%)
		FYVE_RUFY1_like	813..874	CDD:277261	25/63 (40%)
PLEKHF1	XP_005259313.1	PH_Phafin2-like	92..214	CDD:269927	21/126 (17%)
		FYVE_PKHF1	233..296	CDD:277293	28/74 (38%)