Protein Alignment CG31064 and zfyve28a

DIOPT Version :10

• Sequence 1: NP_001287560.1
• Gene: CG31064 / 43277
• FlyBaseID: FBgn0051064
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: NP_001072498.1
• Gene: zfyve28a / 779953
• XenbaseID: XB-GENE-1219057
• Length: 951
• Species: Xenopus tropicalis
• Alignment Length: 839
• Identity: 183/839 - (21%)
• Similarity: 302/839 - (35%)
• Gaps: 250/839 - (29%)

  Fly    88 SATAATPTGTTATAIGATATTRAQAAAAKSQKGQNPPSQQVQPKQQPPQPQQTQQQPLVLQQQQA 152
            :|....|:..:...:.|..|.....|.|::.:.:...|.|..        :|..:|..::..:..
 Frog   297 NADPEVPSAISPVLVTALPTEEPPMAKAENTEVELACSMQYD--------EQELEQLNMMVHRVG 353

  Fly   153 SNSSNTIALPK-----ASHANTSEELA---------GGVQDTIYLCNFRVSVDGEWLCLKELQDI 203
            ...|:.::.|.     |..||||.|.:         ...:|.::.                ::|:
 Frog   354 DEMSSLLSPPSVYQSPAHRANTSNEASPCRRALDNLTDEEDRVFF----------------MEDL 402

  Fly   204 DVAGGTGNQAAQTSEKLAGGSSSQTGGFGSN---YNVGSSSSKRNSKRFSGLSTGSGSGGNAGGG 265
            |.:|          |.||....|:|.....|   ||....:..::|.    |..|..:...:...
 Frog   403 DGSG----------EVLARSRPSETTISWVNNSCYNAKQPALYQDSV----LQNGDLADVVSVKD 453

  Fly   266 GGLDITDNAR-DTAEI--ERSNLVNICKLVVKELLEQSLRYGRMLDSDHLPLQHFFIVIEHVLGH 327
            |..||::|.. |.:::  ..::|.|.|..:  |..|..| |....|::....:...| |.|..|
 Frog   454 GQRDISNNNNIDGSKMLAASASLQNSCSCL--EAPESQL-YLNGWDTNGEDAETAEI-IAHRTG- 513

  Fly   328 GLRPKKGLLGPRKELWDLLQSVEHYCPEAQDITASVRDLPTVRTHIGRARAWLRIALMQKKLSDY 392
            |::....::...|.|.:        .||.....||.| :|:                    .||
 Frog   514 GMKISATVIFNPKSLTN--------SPETSPNLASNR-IPS--------------------SSD- 548

  Fly   393 LQALIEHREDSLFDYYEPHALMMSDEIVVIMGILVGLNVIDCNLCVKEEDL--DSQQGVIDFSLY 455
              .|..:.||      |.|.|.::....:|.         .|..|...||.  ||.:|:
 Frog   549 --PLTSNEED------ESHKLSIAATNCLIN---------SCVCCGSCEDTREDSLEGL------ 590

  Fly   456 LRSSSRNADAAPE-DSAPPALLDATGQGNMIAVLDQKN---YIEELNRHLNATVGNLQAKVESLT 516
                 ||..::.: .:|..:|:.:...|:    ||:.:   ..:||.:..:.||  |.|:.|:..
 Frog   591 -----RNVPSSGKVINASYSLIKSKELGH----LDRSDCTVSAKELLKMDSPTV--LLAEKETTR 644

  Fly   517 TTNALMKEDLAIARNSLLALQAENQAMRQSTSAGDNNSTGSGGSSDKDKEKASEELVE---ERRK 578
            ...........:..||...::.::::....|::.|...:.|......:||:.|||:.|   :|..
 Frog   645 QEQPYPNSSKCLPLNSGSQVEMDSESDEPLTASRDQLRSESNRQETGNKERPSEEVEEPPSDRAS 709

  Fly   579 NSELEKELKLQVSLKAESDMAMKLLEKDIHEKQD-TIVSLRR-------QLDDIKQINLEMYRKL 635
            ...:......|..|:   |.|:..:....:|... |..||..       ..|||.|..:::  .|
 Frog   710 ADNITSSSSSQDGLR---DSALSSISSSDYESVSVTTCSLSSIDSLSSCSSDDIDQEEIQL--AL 769

  Fly   636 QDCKASLTHK--------TELMTKLEVQKEDMASTIDQLEKKWSHDKSNLGEILKTTSQTLTTQV 692
            |..|.:...|        .:|:.:|.|   .::...|||:..::   |:|..||||..:.:.|:
 Frog   770 QAAKIASRQKIRSRFHSSNDLIHRLFV---CISGVADQLQTNYA---SDLRSILKTLFEVMATK- 827

  Fly   693 TASEERAARAEAESRIEREWRISLQEKELKLKEKIAN-------LQGCLKELSEEKERNGKLKAD 750
                                    ||.:.|.|:|.||       |:.|  .|.:|...:.:|.|
 Frog   828 ------------------------QETDDKGKQKKANQGLRSAALEDC--ALCQETITSSELAA- 865

  Fly   751 LDKVRTQWSEAQTTLEELGIQLSVSKLKVSEMQDQERRQRQLLSGSAQSLQAMPEAVGSPGIWAP 815
                                     |.:..|.:|                         |..|.|
 Frog   866 -------------------------KARDGEFED-------------------------PPDWVP 880

  Fly   816 DSIATHCTACEREFNLTRRKHHCRSCGEIFCKACSEHTLPLLNAQGQPGKPVRVCDNCY 874
            |.:.:.||||:..|.:.||||||||||:|||..||.|:.| |...||. ||||||.:||
 Frog   881 DEVCSLCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAP-LPRYGQM-KPVRVCTHCY 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN_RUFY1_like	281..436	CDD:439043	31/154 (20%)
		Smc	<562..>807	CDD:440809	52/270 (19%)
		FYVE_RUFY1_like	813..874	CDD:277261	34/60 (57%)
zfyve28a	NP_001072498.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	360..382		7/21 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	527..557		12/67 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	641..726		15/87 (17%)
		FYVE_LST2	874..938	CDD:277270	38/91 (42%)