Protein Alignment CG31064 and Rufy2

DIOPT Version :10

• Sequence 1: NP_001287560.1
• Gene: CG31064 / 43277
• FlyBaseID: FBgn0051064
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: NP_081701.2
• Gene: Rufy2 / 70432
• MGIID: 1917682
• Length: 606
• Species: Mus musculus
• Alignment Length: 638
• Identity: 263/638 - (41%)
• Similarity: 392/638 - (61%)
• Gaps: 83/638 - (13%)

  Fly   275 RDTAEIERSNLVNICKLVVKELLEQSLRYGRMLDSDHLPLQHFFIVIEHVLGHGLRPKKGLLGPR 339
            :|...:||:||:|:.||.:|.|:|.:|.:||.||||:.|||.||:|:||.|.|||:.:|..|...
Mouse     4 KDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKGRKSFLSYN 68

  Fly   340 KELWDLLQSVEHYCPEAQDITASVRDLPTVRTHIGRARAWLRIALMQKKLSDYLQALIEHREDSL 404
            |.:|..|:.||...|||::|.|||||||.::|.:||||||||:||||||::|||:.||..|| .|
Mouse    69 KTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRE-LL 132

  Fly   405 FDYYEPHALMMSDEIVVIMGILVGLNVIDCNLCVKEEDLDSQQGVIDFSLYLR------SSSRNA 463
            .::||.|||||.:|..||:|:||||||||.|||||.||||||.||||||:||:      :..||.
Mouse   133 SEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEEIGNKERNV 197

  Fly   464 DAAPEDSAPPALLDATGQGNMIAVLDQKNYIEELNRHLNATVGNLQAKVESLTTTNALMKEDLAI 528
            ..|                   |:||||||:|||||.||:||.:|.::|:||..:|..:.|:|||
Mouse   198 QIA-------------------AILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAI 243

  Fly   529 ARNSLLALQAENQAMRQ--------------------STSAGDNNSTGSGGSSDKDKEKASEELV 573
            |:|:::.||.||..:|.                    .|.......:..|  .|:....|..:|.
Mouse   244 AKNNIIKLQEENHQLRSENELILMRTRQHLEVTKVDVETELQTYKHSRQG--LDEMYNDARRQLR 306

  Fly   574 EERRKNSELEKELKLQVSLKAESDMAMKLLEKDIHEKQDTIVSLRRQLDDIKQINLEMYRKLQDC 638
            :|.:...::|.||.:||.:|.|.::|||||||||||||||::.||:||:::|.||:|||::||..
Mouse   307 DESQLRQDVENELSVQVGMKHEMELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQRLQGS 371

  Fly   639 KASLTHKTELMTKLEVQKEDMASTIDQLEKKW-----------SHDKSNLGEILKTTSQTLTTQV 692
            :..|..|.|::.:||.:...:.:.:.|||::.           :.|:....|.| :.|.:|..|:
Mouse   372 EDGLKEKNEIIARLEEKTNKITTAMRQLEQRLQQAEKAQKEAEAEDEKYAQECL-SQSDSLQRQI 435

  Fly   693 TASEERAARAEAESRIEREWRISLQEKELKLKEKIANLQGCLKELSEEKERNGKLKADLDKVRTQ 757
            :..|::..:.|.:.:||:|||.:|||...|.|:.:::|:...:::...|:....|:.:..:::..
Mouse   436 SQKEQQLVQLETDLKIEKEWRQTLQEDLQKEKDVLSHLRHETQKVISLKKEFLNLQDENQQLKRI 500

  Fly   758 WSEAQTTLEELGIQLSVSKLKVSEMQDQERRQRQLLSGSAQSLQAMPEAVGSPGIWAPDSIATHC 822
            :.|.:..|:|||.:|..||||:.::::..:           :||.:        :|..|..||||
Mouse   501 YQEQEQALQELGSKLCESKLKIDDIKEANK-----------ALQGL--------VWLKDKDATHC 546

  Fly   823 TACEREFNLTRRKHHCRSCGEIFCKACSEHTLPLLNAQGQPGKPVRVCDNCYA 875
            ..||:||:|::||||||:||||||.|||::.|||.::.    |||||||:|:|
Mouse   547 KLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSP----KPVRVCDSCHA 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN_RUFY1_like	281..436	CDD:439043	89/154 (58%)
		Smc	<562..>807	CDD:440809	79/255 (31%)
		FYVE_RUFY1_like	813..874	CDD:277261	36/60 (60%)
Rufy2	NP_081701.2	RUN_RUFY2	10..165	CDD:439057	90/155 (58%)
		Smc	<250..>533	CDD:440809	84/296 (28%)
		FYVE_RUFY2	534..604	CDD:277298	38/74 (51%)