Protein Alignment CG31064 and Plekhm2

DIOPT Version :9

• Sequence 1: NP_001287560.1
• Gene: CG31064 / 43277
• FlyBaseID: FBgn0051064
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: NP_001028322.1
• Gene: Plekhm2 / 69582
• MGIID: 1916832
• Length: 1033
• Species: Mus musculus
• Alignment Length: 605
• Identity: 121/605 - (20%)
• Similarity: 199/605 - (32%)
• Gaps: 224/605 - (37%)

  Fly   279 EIERSNLVNICKLVVKELLEQSLRYGRMLDSDHLP--------LQHFFIVIEHVLGHGLRPKKGL 335
            |::...|.|| .|.||:|  ||  |....: |..|        ||.....::|.|.:||:...
Mouse     5 EVKDRILENI-SLSVKKL--QS--YFAACE-DETPAIRNHDKVLQRLCEHLDHALLYGLQDLS-- 61

  Fly   336 LGPRKELWDLLQSVEHYCPEAQDITASVRDLPTVRTHIGRARAWLRIALMQKKLSDYLQALIEHR 400
                ...|.|   |.|:  ..::....:..|..|.|::||:||||.:||.:..|..||: |.:..
Mouse    62 ----SGYWVL---VVHF--TRREAIRQIEVLQHVATNLGRSRAWLYLALNENSLESYLR-LFQEN 116

  Fly   401 EDSLFDYYEPHALMMS-DEIVVIMGILVGLNVIDCNLCVKEEDLDSQQGVIDFSLYLRSSSRNAD 464
            ...|..||..:||:.| |.:.:.:.::.||..|       ..|||.....:|.:.|:
Mouse   117 LGLLQKYYVRNALVCSHDHLTLFLTLVSGLEFI-------RFDLDLDAPYLDLAPYM-------- 166

  Fly   465 AAPEDSAPPALLDATGQGNMIAVLDQKNYIEELNRHLNATVGNLQAKVESLTTTNALMKEDLAIA 529
              |:...|..|||               :.:.|...::.:.........|:|:|| |..:|.|||
Mouse   167 --PDYYKPQYLLD---------------FEDRLPSSVHGSDSLSLNSFNSVTSTN-LEWDDSAIA 213

  Fly   530 RNSLLALQAENQAMRQSTSAGD-NNSTGSGGSSDKDKEKASEELVEERRKNSELEKELKLQVSLK 593
            .:|            :....|| ..:..|..|:|.:
Mouse   214 PSS------------EDYDFGDVFPAVPSVPSTDWE----------------------------- 237

  Fly   594 AESDMAMKLLEKDIHEKQDTIVSLRRQLDDIKQINLEMYRKLQDCKASLTHKTELMTKLEVQKED 658
             :.|:.            |||...|....|:                 .:.||.  ||...|:
Mouse   238 -DGDLT------------DTISGPRSTASDL-----------------TSSKTS--TKSPTQR-- 268

  Fly   659 MASTIDQLEKKWSHDKSNLGEILKTTSQTLTTQVTASEERAARAEAES---------RIEREWRI 714
                         |:..|..:....:|.|.....|:.|:..|:|..:.         |:.::.:|
Mouse   269 -------------HNPFNEEQAETASSDTTPVHTTSQEKEEAQAPDQPDACTELEVIRVTKKKKI 320

  Fly   715 SLQEKELKLKEKIANL------QGCLKE--------------------LSEEKERNGKLKADLDK 753
            . ::|:.||.|..:.|      |.|.::                    |:..:|:...|.:
Mouse   321 G-KKKKTKLDEDASPLHPTSSQQKCGQQGEGDGLVGTPGLARDPSDTVLASPQEQGEGLSS---- 380

  Fly   754 VRTQWSEAQTTLEELGIQLSVSKLKVSEMQDQERRQRQLLSGSAQSLQAMPEAVGSP-------- 810
              |..|...:.|.::|       |.:.||:|...                 |.:|.|
Mouse   381 --TAGSSELSELSQMG-------LLIPEMKDTSM-----------------ECLGQPLSKVIDKL 419

  Fly   811 -GIWAPDSIATHCTACEREF 829
             |...|.:..:|....|:.|
Mouse   420 HGQLDPSTWCSHADPPEQSF 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN	316..439	CDD:280855	33/123 (27%)
		CASP_C	495..>634	CDD:285395	22/139 (16%)
		FYVE_RUFY1_like	813..874	CDD:277261	4/17 (24%)
Plekhm2	NP_001028322.1	RUN	93..156	CDD:214736	23/70 (33%)
		PH	786..887	CDD:278594
		PH_SKIP	787..889	CDD:270119

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839947
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4381
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740