Protein Alignment CG31064 and rufy3

DIOPT Version :9

• Sequence 1: NP_001287560.1
• Gene: CG31064 / 43277
• FlyBaseID: FBgn0051064
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: XP_009299924.1
• Gene: rufy3 / 541522
• ZFINID: ZDB-GENE-050327-58
• Length: 668
• Species: Danio rerio
• Alignment Length: 616
• Identity: 240/616 - (38%)
• Similarity: 361/616 - (58%)
• Gaps: 59/616 - (9%)

  Fly   271 TDNARDTAEIERSNLVNICKLVVKELLEQSLRYGRMLDSDHLPLQHFFIVIEHVLGHGLRPKKGL 335
            |.|.:|...|||.||:|:.||.:|.|:|.:|..||.||||:.|||.||:|:||.|.|||:.||..
Zfish    90 TRNPKDPIAIERLNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKSKKTF 154

  Fly   336 LGPRKELWDLLQSVEHYCPEAQDITASVRDLPTVRTHIGRARAWLRIALMQKKLSDYLQALIEHR 400
            ||..|..|..|:.||...|||.:|||||:|||.::|.:||.|||||:||||||||||::.:| :|
Zfish   155 LGQNKSFWGPLELVEKLTPEAGEITASVKDLPGLKTPLGRGRAWLRLALMQKKLSDYMKTII-NR 218

  Fly   401 EDSLFDYYEPHALMMSDEIVVIMGILVGLNVIDCNLCVKEEDLDSQQGVIDFSLYLRSSSRNADA 465
            :|.|.::|||:||||.:|..||.|:||||||||.|||:|.||||||.||||||:||:..:.::.:
Zfish   219 KDLLGEFYEPNALMMEEEGAVIAGLLVGLNVIDANLCMKGEDLDSQVGVIDFSMYLKDGAHSSKS 283

  Fly   466 APEDSAPPALLDATGQGNMIAVLDQKNYIEELNRHLNATVGNLQAKVESLTTTNALMKEDLAIAR 530
                        ..|.|.:.|:||||||:|||||||:|:|.||||||::|..:|..:.|:||:|.
Zfish   284 ------------TEGDGQITAILDQKNYVEELNRHLSASVNNLQAKVDALEKSNTKLTEELAVAN 336

  Fly   531 NSLLALQAENQAMRQSTS----AGDNNSTGSGGSSDKDKEKASEELVEERRKNSELEKELKLQVS 591
            |.::.||.|.:.:::..|    :....|...|.::.:...:..::|.||.:...::||||:||:.
Zfish   337 NRIITLQEELERVKEEGSYFVESSRKASRADGTANGQVLGETRKQLKEETQLRLDVEKELELQIG 401

  Fly   592 LKAESDMAMKLLEKDIHEKQDTIVSLRRQLDDIKQINLEMYRKLQDCKASLTHKTELMTKLEVQK 656
            :|.|.:::||:|||||.||.|.:|.||:||||::.:|.|:..|.|..::|...|::::.:||.:.
Zfish   402 MKQEMELSMKMLEKDICEKHDALVELRQQLDDVRTLNHELSVKSQSSESSAKQKSDIIGRLEEKT 466

  Fly   657 EDMASTIDQLEKKWSHDKSNLGEILKTTSQTLTTQVTASEERAARAEAESRIEREWRISLQEKEL 721
            ..|.|.|.|||.:..  |:.....|...:..|..|....:..:.:.|.|....:.|   :.|:||
Zfish   467 NQMGSIIKQLESRCK--KAERERDLADEANRLFKQEFGDKIESLQTEVEQLRRQRW---ILEQEL 526

  Fly   722 KLKEKIANLQ--GCLKELSEEKERNGK-----LKADLDKVRTQWSEAQTTLEELGIQLSVSKLKV 779
            |.......:|  ..|...:..::|:.|     ::.:|:.|:.:....:|.|||   :.|:|....
Zfish   527 KKGRDHPGVQTPETLLGKTPPQQRDSKQHIEDIRKELESVKKENDTLRTALEE---KTSLSSSLT 588

  Fly   780 SEMQDQERRQRQLLSGSAQSLQAMPEAVGSPGIWAPDSIATHCTACEREFNLTRRKHHCRSCGEI 844
            ...:|::.             |::.:.| .|.|         ||.||.:.:||..|..|::|..:
Zfish   589 LSHEDEQN-------------QSLCKEV-DPSI---------CTMCENQDSLTSPKSQCKNCSGV 630

  Fly   845 FCKACSEHTLPLLNAQGQPGKPVRVCDNCYA 875
            ||:.|..:.|||.::.    .|..|||.||:
Zfish   631 FCENCMANELPLPSSI----NPEHVCDVCYS 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN	316..439	CDD:280855	73/122 (60%)
		CASP_C	495..>634	CDD:285395	58/142 (41%)
		FYVE_RUFY1_like	813..874	CDD:277261	19/60 (32%)
rufy3	XP_009299924.1	RUN	135..258	CDD:280855	73/123 (59%)
		TTKRSYEDQ	<306..350	CDD:287216	20/43 (47%)
		FYVE_RUFY3	607..656	CDD:277283	20/61 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584049
Domainoid	1	1.000	150	1.000	Domainoid score	I4349
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D329099at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24555
orthoMCL	1	0.900	-	-		OOG6_103035
Panther	1	1.100	-	-	O	PTHR45956
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5167
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.880