Protein Alignment CG31064 and Rufy3

DIOPT Version :9

• Sequence 1: NP_001287560.1
• Gene: CG31064 / 43277
• FlyBaseID: FBgn0051064
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: XP_006535172.1
• Gene: Rufy3 / 52822
• MGIID: 106484
• Length: 687
• Species: Mus musculus
• Alignment Length: 646
• Identity: 250/646 - (38%)
• Similarity: 363/646 - (56%)
• Gaps: 99/646 - (15%)

  Fly   258 SGGNAGGGGG------LDITDNARDTAE-------IERSNLVNICKLVVKELLEQSLRYGRMLDS 309
            |||:.|||..      .|:.:..|...|       .||.||:|:.||.:|.|:|.:|..||.|||
Mouse   100 SGGSGGGGKHHSWEDLTDLVEQVRADPEDPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDS 164

  Fly   310 DHLPLQHFFIVIEHVLGHGLRPKKGLLGPRKELWDLLQSVEHYCPEAQDITASVRDLPTVRTHIG 374
            |:.|||.||:|:||.|.|||:.||..||..|..|..|:.||...|||.:|||||:|||.::|.:|
Mouse   165 DYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVG 229

  Fly   375 RARAWLRIALMQKKLSDYLQALIEHREDSLFDYYEPHALMMSDEIVVIMGILVGLNVIDCNLCVK 439
            |.|||||:||||||||:|::||| ::::.|.::||.:||||.:|..:|.|:||||||||.|.|:|
Mouse   230 RGRAWLRLALMQKKLSEYMKALI-NKKELLSEFYEVNALMMEEEGAIIAGLLVGLNVIDANFCMK 293

  Fly   440 EEDLDSQQGVIDFSLYLR--SSSRNADAAPEDSAPPALLDATGQGNMIAVLDQKNYIEELNRHLN 502
            .||||||.||||||:||:  :||:.::               |.|.:.|:||||||:||||||||
Mouse   294 GEDLDSQVGVIDFSMYLKDGNSSKGSE---------------GDGQITAILDQKNYVEELNRHLN 343

  Fly   503 ATVGNLQAKVESLTTTNALMKEDLAIARNSLLALQAENQAMRQSTSAGDNNSTGSGGSSDKDKE- 566
            |||.|||.||:.|..:|..:.|:||:|.|.::.||.|.:.:::.:|. ...|...|...|:..|
Mouse   344 ATVNNLQTKVDLLEKSNTKLTEELAVANNRIITLQEEMERVKEESSY-LLESNRKGPKQDRTAEG 407

  Fly   567 ----KASEELVEERRKNSELEKELKLQVSLKAESDMAMKLLEKDIHEKQDTIVSLRRQLDDIKQI 627
                :|.:.|.||.:...::||||:||:|::.|.::|||:||||:.||||.:||||:||||::.:
Mouse   408 QALSEARKHLKEETQLRLDVEKELELQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRAL 472

  Fly   628 NLEMYRKLQDCKASLTHKTELMTKLEVQKEDMASTIDQLEKKWSHDKSNLGEILKTTSQTLTTQV 692
            ..|:..|||.....:..|:||.::||.:...||:||.|||::..  ::..|.........|..|.
Mouse   473 KHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLR--QAERGRQSAELDNRLFKQD 535

  Fly   693 TASEERAARAEAESRIEREWRISL---QEKELKLKEKIANLQGCLK-ELSEE-----KERNGKLK 748
            ...:..:.:.|.|:...:..::.|   ||||.|.:.:....:|..| ||..:     :|.|.|||
Mouse   536 FGDKINSLQLEVEALTRQRTQLELELKQEKERKSQNRGTPGKGAQKPELRMDGKHRIQEENVKLK 600

  Fly   749 ADLDKVRTQWSEAQTTLEELGIQLSVSKLKVSEMQDQERRQRQLLSGSAQSLQAMPEAVGSPGIW 813
            ..|::                                   ..:||:..|:. |..|.....|.:
Mouse   601 KPLEE-----------------------------------SHRLLTHPAEE-QGQPSLSEKPQV- 628

  Fly   814 APDSIATHCTACEREFNLTRRKHHCRSCGEIFCKACSEHTLPLLNAQGQPGKPVRVCDNCY 874
                    |..|:.:.:||  |:.||:|...||.||:.:.|||.::.    ||.|||:.|:
Mouse   629 --------CQLCQEDDSLT--KNTCRNCRGTFCNACTTNELPLPSSI----KPERVCNPCH 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN	316..439	CDD:280855	69/122 (57%)
		CASP_C	495..>634	CDD:285395	63/143 (44%)
		FYVE_RUFY1_like	813..874	CDD:277261	20/60 (33%)
Rufy3	XP_006535172.1	RUN	171..292	CDD:367169	68/121 (56%)
		Smc	<340..>570	CDD:224117	85/232 (37%)
		FYVE_RUFY3	629..675	CDD:277283	20/51 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839946
Domainoid	1	1.000	146	1.000	Domainoid score	I4515
eggNOG	1	0.900	-	-		E1_KOG4381
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42809
orthoMCL	1	0.900	-	-		OOG6_103035
Panther	1	1.100	-	-	O	PTHR45956
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5167
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730