DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31064 and Rundc3a

DIOPT Version :9

Sequence 1:	NP_001287560.1	Gene:	CG31064 / 43277	FlyBaseID:	FBgn0051064	Length:	877	Species:	Drosophila melanogaster
Sequence 2:	XP_006533751.1	Gene:	Rundc3a / 51799	MGIID:	1858752	Length:	465	Species:	Mus musculus

Alignment Length:	404	Identity:	103/404 - (25%)
Similarity:	164/404 - (40%)	Gaps:	114/404 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   280 IERSNLVNICKLVVKELLEQSLRY-GRMLDSDHLPLQHFFIVIEHVLGHGLRPKKGL-------- 335
            :||.||:.:|:..||.|||   :| ...:|.......:|..::|.:|.|..   ||:
Mouse    26 VERRNLITVCRFSVKTLLE---KYTAEPIDDSSEEFVNFAAILEQILSHRF---KGIAESPPCPG 84

  Fly   336 -----LGP--------RKELWDLLQ----SVEHYCPEAQDITASVRDLPTVRTHIGRARAWLRIA 383
                 .||        ::..||.::    .|.:.|      .:|:.::..:.|...:.|||:|:|
Mouse    85 SACAPAGPASWFSSDGQRGFWDYIRLACSKVPNNC------VSSIENMENISTARAKGRAWIRVA 143

  Fly   384 LMQKKLSDYL-QALIEHREDSLFDYYEPHALMMSDEIVVIMGILVGLNVIDCNLCVKEEDLDSQQ 447
            ||:|::|:|: .||.::|....|  |:..|:|:.:|..|:.|:|:||:.||.:.|:|.|.||.:.
Mouse   144 LMEKRMSEYITTALRDNRTTRRF--YDSGAIMLREEATVLTGMLIGLSAIDFSFCLKGEVLDGKT 206

  Fly   448 G-VIDFSLYLR-----------------SSSRNADAAPEDSAPPALLDATGQGN--------MIA 486
            . |||::.||:                 .||.:.|.:||....|.:.|.....|        ...
Mouse   207 PVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYNKWHKMEQKFRI 271

  Fly   487 VLDQKNYIEELNR-------HLNATVGNLQAKVESLTTTNALMKEDLAIARNSLLALQAE----N 540
            |..||.|:|||.|       .|.|....||.::|.....|...|.:|   ...:|.||.:    .
Mouse   272 VYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKREL---EGVILELQEQLPDPP 333

  Fly   541 QAMRQSTSAGDNNSTGSGGSSDKDKEKASEELV---------------EERRKNSELEKE----- 585
            ...|.....||:.....|          |:||.               .|...||:|.:.
Mouse   334 PPPRTGLIPGDHAPLAQG----------SKELTTSLVNQWPSLSTLHRPEGASNSKLYRRHSFMS 388

  Fly   586 ---LKLQVSLKAES 596
               |..:.||.::|
Mouse   389 TEPLSAEASLSSDS 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN	316..439	CDD:280855	40/148 (27%)
		CASP_C	495..>634	CDD:285395	30/136 (22%)
		FYVE_RUFY1_like	813..874	CDD:277261
Rundc3a	XP_006533751.1	RUN	60..197	CDD:367169	39/147 (27%)
Rundc3a	XP_006533751.1	UPF0242	<266..>329	CDD:369080	19/65 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839952
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4381
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740