DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31064 and plekhf1

DIOPT Version :9

Sequence 1:	NP_001287560.1	Gene:	CG31064 / 43277	FlyBaseID:	FBgn0051064	Length:	877	Species:	Drosophila melanogaster
Sequence 2:	NP_956634.1	Gene:	plekhf1 / 393311	ZFINID:	ZDB-GENE-040426-1289	Length:	293	Species:	Danio rerio

Alignment Length:	223	Identity:	57/223 - (25%)
Similarity:	95/223 - (42%)	Gaps:	22/223 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   657 EDMASTIDQLEKKWSHDKS--NLGEILKTTSQTLTTQVTASEERAARAEAESRIEREWRISLQEK 719
            |.:|.||...|:..:.:.|  ..|::|:...:.|..:  ...::..|...:.|:...:...|...
Zfish     3 EHLAFTIQNRERIQAVESSFGRTGKMLQKPGRFLVGE--GCLQKLCRRGPQPRVFYLFNDILVYG 65

  Fly   720 ELKLKEKIANLQGC--LKELSEEKERNGKLKADLDKVRTQWSEAQTTLEELGIQLSVSKLKVSEM 782
            .:.|..:..|.|..  |:|:.:|...:|...|:      ||. .:|..:...:.....:.|::.|
Zfish    66 SIMLHGRWNNKQNIIPLEEVQQEDLEDGMAMAN------QWL-IRTPRKSFYVSAESPEEKIAWM 123

  Fly   783 QDQERRQRQLLSGSAQSLQAMPEAVGSPGIWAPDSIATHCTACEREFNLTRRKHHCRSCGEIFCK 847
            ...|  |.:.|....:.|.|..........|.||..:..|..|.:.|.:..|:||||.||.|.|:
Zfish   124 GHIE--QYRTLHVKNKGLPAKKSGDDFATPWIPDVASAICMRCSKRFTVANRRHHCRRCGYIVCQ 186

  Fly   848 ACSE--HTLPLLNAQGQPGKPVRVCDNC 873
            |||:  ..||.::     .:|||||.||
Zfish   187 ACSKGRAVLPHIS-----NRPVRVCRNC 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN	316..439	CDD:280855
		CASP_C	495..>634	CDD:285395
		FYVE_RUFY1_like	813..874	CDD:277261	27/63 (43%)
plekhf1	NP_956634.1	PH_Phafin2-like	7..129	CDD:269927	24/132 (18%)
		PH	39..128	CDD:278594	17/99 (17%)
		PHD_SF	151..209	CDD:304600	25/62 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584056
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840